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Xi'an Shiyou University

2 ARTICLES PUBLISHED IN JoVE

Bioengineering

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Fenfang Li¹, Fang Yuan², Georgy Sankin¹, Chen Yang¹, Pei Zhong¹

¹Mechanical Engineering and Materials Science, Duke University, ²Huacells Corp

A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.

Engineering

Evaluation of an Exclusive Spur Dike U-Turn Design with Radar-Collected Data and Simulation

Yang Shao¹, Hongtao Yu¹, Huan Wu², Xueyan Han¹, Xizhen Zhou¹, Christian G. Claudel³, Hualing Zhang⁴, Chen Yang⁵

¹Highway Academy, Chang'an University, ²Human Resource Department, Xi'an Shiyou University, ³Cockrell School of Engineering, University of Texas at Austin, ⁴Department of Earth and Atmospheric Science, University of Houston, ⁵School of Foreign Languages, Xi'an Shiyou University

This protocol describes the process of solving a microscopic traffic problem with simulation. The whole process contains a detailed description of data collection, data analysis, simulation model build, simulation calibration, and sensitive analysis. Modifications and troubleshooting of the method are also discussed.