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Mackay Medical College

4 ARTICLES PUBLISHED IN JoVE

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Medicine

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection
Chun-Nin Lee 1, Li-Hsuan Chiu 2,5, Chia-Lang Fang 3, Shauh-Der Yeh 4, Chun S. Zuo 5, Shih-Ching Chen 6, Li-Kuo Kuo 7, Yun-Ming Wang 8, Wen-Fu Thomas Lai 2,5,9
1Department of Pulmonary and Critical Care Medicine, Taipei Medical University-Shuang Ho Hospital, 2Department of Research and Department of Dentistry, Taipei Medical University / Shuang-Ho Hospital, 3Department of Pathology, Taipei Medical University, 4Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, 5McLean Imaging Center, McLean Hospital/Harvard Medical School, 6Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, 7Department of Medicine, Mackay Medical College, 8Department of Biological Science and Technology, National Chiao Tung University, 9Graduate Institute of Clinical Medicine, Taipei Medical University

To improve serological diagnostic tests for Mycobacterium tuberculosis antigens, we developed superparamagnetic iron oxide nanoprobes to detect extrapulmonary tuberculosis.

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Medicine

An Endoscopic Transcanal Transpromontorial Approach for Vestibular Schwannomas using a Computer-Based Three-Dimensional Imaging System
Chin-Kuo Chen 1, Li-Chun Hsieh 2,3, Yu-Jen Lu 4, Chu-Po Lin 5
1Department of Otolaryngology-Head and Neck Surgery and Communication Enhancement Center, Chang Gung Memorial Hospital and Chang Gung University, 2Department of Otolaryngology-Head and Neck Surgery, Mackay Memorial Hospital, 3Department of Audiology and Speech Language Pathology, Mackay Medical College, 4Department of Neurosurgery, Chang Gung Memorial Hospital and Chang Gung University, 5Department of Medical Education, Chang Gung Memorial Hospital and Chang Gung University

Here, we present a transcanal transpromontorial approach for vestibular schwannomas using a computer-based three-dimensional (3D) imaging system combined with a two-dimensional (2D) endoscope. This system provided stereoscopic vision, better depth perception and reduced visual fatigue. This 3D imaging system enabled the application of 3D vision technology in endoscopic lateral skull base surgery.

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Medicine

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Hui-Chun Ku 1, Ding-Kuo Chien 2,3,4,5, Chuan-Lei Chao 5,6, Shih-Yi Lee 5,7
1Department of Life Science, Fu Jen Catholic University, 2Department of Medicine, MacKay Medical College, 3Department of Emergency Medicine, MacKay Memorial Hospital, 4Graduate Institute of Injury Prevention and Control, Taipei Medical University, 5MacKay Junior College of Medicine, Nursing, and Management, 6Division of Cardiology, Department of Internal Medicine, Taitung Mackay Memorial Hospital, 7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, MacKay Memorial Hospital

Herein, we present a protocol focusing on the quality control of the left anterior descending coronary artery ligation by technically modifying the traditional procedure in rats for acute myocardial ischemia-reperfusion research.

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Neuroscience

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Dian-Shiue Lee 1, Yu-Ling Pan 1, Yi-Chao Hsu 1,2
1Department of Audiology and Speech-Language Pathology, MacKay Medical College, 2Institute of Biomedical Sciences, MacKay Medical College

Here, we present a protocol for a mouse model of noise-induced hearing loss (NIHL). To induce NIHL, we developed a new and simple device using corrugated plastic, a rat trap cage, and a speaker. Auditory brainstem response and immunofluorescence imaging were employed to assess the hearing function and outer hair cell damage, respectively.

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