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Chapter 2

Efeitos Adversos de Medicamentos e Toxicidade Química

Farmacovigilância
Farmacovigilância
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug ...
Dependência de Medicamentos
Dependência de Medicamentos
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting ...
Efeitos de Substâncias Químicas: Visão Geral
Efeitos de Substâncias Químicas: Visão Geral
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in ...
Tipos de Toxinas
Tipos de Toxinas
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or ...
Reações Tóxicas: Visão Geral
Reações Tóxicas: Visão Geral
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive ...
Reações Alérgicas a Medicamentos
Reações Alérgicas a Medicamentos
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic ...
Teratogenicidade
Teratogenicidade
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and ...
Mutagenicidade e Carcinogenicidade
Mutagenicidade e Carcinogenicidade
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for ...
Antídotos
Antídotos
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely ...
Prevenção da Absorção Adicional de Veneno
Prevenção da Absorção Adicional de Veneno
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using ...
Eliminação Aumentada de Veneno
Eliminação Aumentada de Veneno
Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures. Antidotes serve a crucial role in ...
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