Chapter 6
Principles of Mass Spectrometry
Espectrometria de massa: visão geral
Mass spectrometry is an analytical technique used to determine the molecular mass and molecular formula of a compound. The basic principle of mass ...
Espectrometria de massa: efeito isotópico
Most elements exist in nature as a mixture of isotopes. The isotopes differ in weight due to their respective number of neutrons. The molecular weight of ...
Espectrometria de Massa: Visão Geral da Fragmentação Molecular
The ionization of a molecule into a molecular ion inside the mass spectrometer causes instability in the molecule's structure due to the loss of an ...
Espectrômetros de massa
This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record ...
Espectro de massa
A mass spectrum is the graphical representation of the relative abundance of the charged fragments in an analyte plotted against their mass-to-charge ...
Espectro de massa: interpretação
Given a known molecular ion mass, the unknown compound can be identified.
The empirical formula is determined from the molecular ion mass and the isotope ...
Analisadores de massa: visão geral
Common mass analyzers include magnetic sector, double-focusing, quadrupole, time-of-flight, and ion trap analyzers.
The capability of any mass analyzer ...
Analisadores de massa: tipos comuns
The quadrupole mass analyzer consists of four parallel rods, across which are applied a DC voltage and a radio-frequency AC voltage.
Here, the field ...
Espectrometria de Massa de Alta Resolução (HRMS)
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the ...
Espectrometria de Massa: Análise Complexa
The analysis of complex mixtures requires the combination of separation methods and mass spectrometry in sequence, termed hyphenated methods.
GC–MS ...
Espectrometria de massa em tandem
Tandem mass spectrometry, or MS/MS, combines two mass analyzers in sequence, connected by a collision or interaction cell.
First, the samples are ionized ...
Cromatografia Gasosa – Espectrometria de Massa (GC–MS)
Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a ...
Espectrometria de Massa com Plasma Indutivamente Acoplado (ICP-MS): Visão Geral
Inductively coupled plasma–mass spectrometry, or ICP–MS, uses an ICP source to prepare samples for atomic mass spectrometry.
Solution-state ...
Espectrometria de Massa com Plasma Indutivamente Acoplado (ICP-MS): Interferências
Despite the advantages offered by ICP–MS, accurate elemental analysis is affected by spectroscopic and non-spectroscopic interferences.
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