Invasion Assay: "3D" Embedding of Glioma and Macrophages or Microglia in Matrix
6:14
Results: Microglia and Macrophage Enhancement of Glioblastoma Cell Invasion
8:42
Conclusion
TRANSCRIÇÃO
The overall goal of this experiment is to model the interaction of glioblastoma cells with microglia and macrophages during invasion in an in vitro assay. So this method can help answer key questions in the tumor microenvironment field, such as wh
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Understanding the malignant behavior of cancer requires creating accurate models of how tumor cells interact with components of the tumor microenvironment, such as macrophages. Here we describe two methods to study glioblastoma cell interaction with tumor associated macrophages and microglia where the effect on glioblastoma invasion is assessed.