Radiolabeling of Tetrazines via Chelation to 99mTc
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Pre-targeted Biodistribution Studies
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Results: Bio-distribution of 99mTc-labeled Tetrazine Complexes
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Conclusion
Transcrição
The overall goal of this procedure is to produce technetium-99m labeled tetrazines for pre-targeted imaging using bioorthogonal chemistry with trans-cyclooctene modified biomolecules as targeting vectors. This method provides an important new plat
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Here, we describe a protocol for radiolabeling and in vivo testing of tridentate 99mTc(I) chelate-tetrazine derivatives for pre-targeting and bioorthogonal chemistry.