Department of Biochemistry
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The Central Polybasic Region of the Soluble SNARE (Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor) Vam7 Affects Binding to Phosphatidylinositol 3-Phosphate by the PX (Phox Homology) Domain.
The Journal of biological chemistry 08, 2016 | Pubmed ID: 27365394
Use of Microscale Thermophoresis (MST) to Measure Binding Affinities of Components of the Fusion Machinery.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30317505
Use of Surface Plasmon Resonance (SPR) to Determine Binding Affinities and Kinetic Parameters Between Components Important in Fusion Machinery.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30317506
Phosphatidic acid induces conformational changes in Sec18 protomers that prevent SNARE priming.
The Journal of biological chemistry 03, 2019 | Pubmed ID: 30617180
A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
The Journal of biological chemistry 11, 2019 | Pubmed ID: 31515268
An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes.
Biochemistry 11, 2020 | Pubmed ID: 33153264
University of Illinois at Urbana-Champaign
Robert P. Sparks*,1,
William Lawless*,2,
Andres S. Arango*,1,3,4,
Emad Tajkhorshid1,3,4,
Rutilio A. Fratti1,3
1Department of Biochemistry, University of Illinois at Urbana-Champaign,
2Department of Chemistry, University of South Florida,
3Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign,
4Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
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