Rakesh Karmacharya

Harvard Stem Cell Institute

Affiliated withHarvard Stem Cell Institute Massachusetts General Hospital Broad Institute of MIT and Harvard

Research Area

Neuroscience

Biography

JoVE Journal Publications

Article Total : 2	Year
Publication title	2020
Publication title	2021

Other Publications

Article	Year
Principles and neurobiological correlates of concentrative, diffuse, and insight meditation. Harvard review of psychiatry\| PubMed ID: 24651509	2013
HDAC6 inhibitors modulate Lys49 acetylation and membrane localization of β-catenin in human iPSC-derived neuronal cells. ACS chemical biology\| PubMed ID: 25546293	2015
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. Cell reports\| PubMed ID: 25660025	2015
Effects of LEP, LEPR, ADIPOQ, MC4R and FTO polymorphisms on dyslipidemia in Korean patients with schizophrenia who are taking clozapine. Psychiatry research\| PubMed ID: 25841316	2015
Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells. Molecular and cellular neurosciences\| PubMed ID: 26777134	2016
Stem cell models of neuropsychiatric disorders. Molecular and cellular neurosciences\| PubMed ID: 27013423	2016
Gene Expression-Based Screen for Parkinson's Disease Identifies GW8510 as a Neuroprotective Agent. ACS chemical neuroscience\| PubMed ID: 27270122	2016
Perturbational Profiling of Metabolites in Patient Fibroblasts Implicates α-Aminoadipate as a Potential Biomarker for Bipolar Disorder. Molecular neuropsychiatry\| PubMed ID: 27606323	2016
Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines. Journal of proteome research\| PubMed ID: 28152600	2017
Stem cell-derived neurons in the development of targeted treatment for schizophrenia and bipolar disorder. Pharmacogenomics\| PubMed ID: 28346060	2017
Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. ACS chemical biology\| PubMed ID: 28628306	2017
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning. Nature neuroscience\| PubMed ID: 30718903	2019
Identifying depression early in adolescence. The Lancet. Child & adolescent health\| PubMed ID: 30878111	2019
HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem-Cell-Derived Neurons. International journal of molecular sciences\| PubMed ID: 30935091	2019
Protocol for a systematic review of the development of depression among adolescents and young adults: psychological, biological, and contextual perspectives around the world. Systematic reviews\| PubMed ID: 31325965	2019
Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine. Translational psychiatry\| PubMed ID: 31780643	2019
Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia. JAMA psychiatry\| PubMed ID: 32186681	2020
Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder. Genome medicine\| PubMed ID: 32306996	2020
Integrating stem cell-based experiments in clinical research. European psychiatry : the journal of the Association of European Psychiatrists\| PubMed ID: 32536357	2020
Advances toward precision medicine for bipolar disorder: mechanisms & molecules. Molecular psychiatry\| PubMed ID: 32636474	2020
Mental Health Units in Correctional Facilities in the United States. Harvard review of psychiatry\| PubMed ID: 32692089	2020
Comparative Transcriptomic Analysis of Cerebral Organoids and Cortical Neuron Cultures Derived from Human Induced Pluripotent Stem Cells. Stem cells and development\| PubMed ID: 32862797	2020
A systematic review of the association between biological markers and environmental stress risk factors for adolescent depression. Journal of psychiatric research\| PubMed ID: 33857787	2021
The Identifying Depression Early in Adolescence Risk Stratified Cohort (IDEA-RiSCo): Rationale, Methods, and Baseline Characteristics. Frontiers in psychiatry\| PubMed ID: 34234702	2021