Janis Kuka

Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart.

Myocardial infarct size-limiting and anti-arrhythmic effects of mildronate orotate in the rat heart.

Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.

Effects of long-term mildronate treatment on cardiac and liver functions in rats.

Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism.

Mildronate treatment alters γ-butyrobetaine and l-carnitine concentrations in healthy volunteers.

Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats.

The cardioprotective effect of mildronate is diminished after co-treatment with L-carnitine.

A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function.

Troubleshooting digital macro photography for image acquisition and the analysis of biological samples.

Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion.

The heart is better protected against myocardial infarction in the fed state compared to the fasted state.

Magnesium nitrate attenuates blood pressure rise in SHR rats.

Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size.

Long-chain acylcarnitine content determines the pattern of energy metabolism in cardiac mitochondria.

Expression and purification of active, stabilized trimethyllysine hydroxylase.

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.

Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis.

Structure and Function of CutC Choline Lyase from Human Microbiota Bacterium Klebsiella pneumoniae.

Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance.

Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity.

Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria.

Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB.

Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice.

Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues.

Skull Fractures Induce Neuroinflammation and Worsen Outcomes after Closed Head Injury in Mice.

Excretion of the Polymyxin Derivative NAB739 in Murine Urine.

Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload.

Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice.

Inhibition of CPT2 exacerbates cardiac dysfunction and inflammation in experimental endotoxaemia.

-Fluorine Effect in Cyclopropane: Diastereoselective Synthesis of Fluorocyclopropyl Cabozantinib Analogs.

Inhibition of Fatty Acid Metabolism Increases EPA and DHA Levels and Protects against Myocardial Ischaemia-Reperfusion Injury in Zucker Rats.

Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage.

Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.