Sandrine Delbosc

Simvastatin prevents angiotensin II-induced cardiac alteration and oxidative stress.

Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes.

Sodium restriction prevents cardiac hypertrophy and oxidative stress in angiotensin II hypertension.

Superoxide anion overproduction in sepsis: effects of vitamin e and simvastatin.

Red wine polyphenols alone or in association with ethanol prevent hypertension, cardiac hypertrophy, and production of reactive oxygen species in the insulin-resistant fructose-fed rat.

Extracts enriched in different polyphenolic families normalize increased cardiac NADPH oxidase expression while having differential effects on insulin resistance, hypertension, and cardiac hypertrophy in high-fructose-fed rats.

Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.

Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat.

Overproduction of reactive oxygen species in end-stage renal disease patients: a potential component of hemodialysis-associated inflammation.

Modulation of CD36 protein expression by AGEs and insulin in aortic VSMCs from diabetic and non-diabetic rats.

Cardiovascular biomarker discovery by SELDI-TOF mass spectrometry.

Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.

The benefit of docosahexanoic acid on the migration of vascular smooth muscle cells is partially dependent on Notch regulation of MMP-2/-9.

Proteomic analysis permits the identification of new biomarkers of arterial wall remodeling in hypertension.

Protective effect of high-density lipoprotein-based therapy in a model of embolic stroke.

Proteins associated with the size and expansion rate of the abdominal aortic aneurysm wall as identified by proteomic analysis.

Identification of peroxiredoxin-1 as a novel biomarker of abdominal aortic aneurysm.

Porphyromonas gingivalis participates in pathogenesis of human abdominal aortic aneurysm by neutrophil activation. Proof of concept in rats.

In vitro and in vivo evidence for the role of elastase shedding of CD163 in human atherothrombosis.

From intraplaque haemorrhages to plaque vulnerability: biological consequences of intraplaque haemorrhages.

Role of vegetation-associated protease activity in valve destruction in human infective endocarditis.

Fucoidan interferes with Porphyromonas gingivalis-induced aneurysm enlargement by decreasing neutrophil activation.

High-density lipoprotein-based therapy reduces the hemorrhagic complications associated with tissue plasminogen activator treatment in experimental stroke.

Predominant role of host proteases in myocardial damage associated with infectious endocarditis induced by Enterococcus faecalis in a rat model.