Universidad Nacional Autónoma de Mexico (UNAM)
2 ARTICLES PUBLISHED IN JoVE
Medicine
Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
Benjamín León-Mancilla 1,2, Moisés Martínez-Castillo 1, Zaira Medina-Avila 1, Armando Pérez-Torres 3, Jorge Garcia-Loya 2, Ana Alfaro-Cruz 4, Cristina Piña-Barba 5, Gabriela Gutierrez-Reyes 1
1Liver, Pancreas and Motility Laboratory; Unit of Experimental Medicine; School of Medicine, Universidad Nacional Autónoma de Mexico (UNAM), 2Department of Surgery, School of Medicine, Universidad Nacional Autónoma de México (UNAM), 3Department of Cells and Tissue Biology, School of Medicine, Universidad Nacional Autónoma de México (UNAM), 4Department of Pathology, Hospital General de Mexico, 5Materials Research Institute, Universidad Nacional Autónoma de México (UNAM)
Liver diseases are induced by many causes that promote fibrosis or cirrhosis. Transplantation is the only option for recovering health. However, given the scarcity of transplantable organs, alternatives must be explored. Our research proposes the implantation of collagen scaffolds in liver tissue from an animal model.
Immunology and Infection
Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar
Betsaida J. Ortiz-Sánchez 1,2, Imelda Juárez Avelar 2,3, Miriam Rodriguez-Sosa 2
1Undergraduate Program of Dental Surgeon, Facultad de Estudios Superiores Iztacala (FES-Iztacala), Universidad Nacional Autónoma de Mexico (UNAM), 2Innate Immunity Laboratory, Biomedicine Research Unit (UBIMED), FES-Iztacala, UNAM, 3Doctoral Program in Biological Sciences, UNAM
This study describes a modified 6-0 nylon ligation method for inducing periodontitis in mice, which is highly reproducible and represents an alternative for researchers to study periodontal disease from its development to its pathological consequences.
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