Tiziana Bonaldi

The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding.

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion.

The use of mass spectrometry for the analysis of histone modifications.

The N-terminus of Drosophila SU(VAR)3-9 mediates dimerization and regulates its methyltransferase activity.

A combination of different mass spectroscopic techniques for the analysis of dynamic changes of histone modifications.

The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes.

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.

Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9.

"Chromatomics" the analysis of the chromatome.

PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state.

Site-specific acetylation of ISWI by GCN5.

Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry.

Quantitative proteomics as a new piece of the systems biology puzzle.

Combined use of RNAi and quantitative proteomics to study gene function in Drosophila.

Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics.

The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin.

SILAC-based proteomic analysis to dissect the "histone modification signature" of human breast cancer cells.

Systems biology "on-the-fly": SILAC-based quantitative proteomics and RNAi approach in Drosophila melanogaster.

Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.

Yin Yang 1 extends the Myc-related transcription factors network in embryonic stem cells.

Methylation of CenH3 arginine 37 regulates kinetochore integrity and chromosome segregation.

The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components.

Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.

Reply to "Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases".

Mass spectrometry-based proteomics for the analysis of chromatin structure and dynamics.

Cell reprogramming requires silencing of a core subset of polycomb targets.

Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome.

Threshold-controlled ubiquitination of the EGFR directs receptor fate.

Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity.

Biochemical systems approaches for the analysis of histone modification readout.

Quantitative chemical proteomics identifies novel targets of the anti-cancer multi-kinase inhibitor E-3810.

Proteomics meets genetics: SILAC labeling of Drosophila melanogaster larvae and cells for in vivo functional studies.

Improved bottom-up strategy to efficiently separate hypermodified histone peptides through ultra-HPLC separation on a bench top Orbitrap instrument.

ARGONAUTE2 cooperates with SWI/SNF complex to determine nucleosome occupancy at human Transcription Start Sites.

Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth.

Pathology Tissue-quantitative Mass Spectrometry Analysis to Profile Histone Post-translational Modification Patterns in Patient Samples.

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth.

The contribution of mass spectrometry-based proteomics to understanding epigenetics.

Recent advances in mass spectrometry analysis of histone post-translational modifications: potential clinical impact of the PAT-H-MS approach.

MS-analysis of SILAC-labeled MYC-driven B lymphoma cells overexpressing miR-17-19b.

MYC/miR-17-92 interplay maintains B-lymphoma cell homeostasis.

The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death.

Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case.

Quantitative assessment of chemical artefacts produced by propionylation of histones prior to mass spectrometry analysis.

Mass-spectrometry analysis of histone post-translational modifications in pathology tissue using the PAT-H-MS approach.

SILAC-Based Quantitative Strategies for Accurate Histone Posttranslational Modification Profiling Across Multiple Biological Samples.

High constitutive activity of a broad panel of housekeeping and tissue-specific -regulatory elements depends on a subset of ETS proteins.

PAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples.

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

Chromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers.

A role for CENP-A/Cse4 phosphorylation on serine 33 in deposition at the centromere.

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases.

PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN-Inducible Proteins.

Zc3h10 is a novel mitochondrial regulator.

Extensive and systematic rewiring of histone post-translational modifications in cancer model systems.

The kinetochore module Okp1/Ame1 is a reader for N-terminal modifications on the centromeric histone Cse4.

Mass Spectrometry-Based Proteomics to Unveil the Non-coding RNA World.

Alternative digestion approaches improve histone modification mapping by mass spectrometry in clinical samples.

hmSEEKER: Identification of hmSILAC Doublets in MaxQuant Output Data.

Proteomics profiling of arginine methylation defines PRMT5 substrate specificity.

Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer.

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.

hSWATH: Unlocking SWATH's Full Potential for an Untargeted Histone Perspective.

Epigenetic drug target deconvolution by mass spectrometry-based technologies.

Enrichment of histones from patient samples for mass spectrometry-based analysis of post-translational modifications.

PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis.

PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin.

Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.

Biochemical and Computational Approaches for the Large-Scale Analysis of Protein Arginine Methylation by Mass Spectrometry.

Clinical Application of Mass Spectrometry-Based Proteomics in Lung Cancer Early Diagnosis.

Software Options for the Analysis of MS-Proteomic Data.

Spatial epi-proteomics enabled by histone post-translational modification analysis from low-abundance clinical samples.

Native Chromatin Proteomics (N-ChroP) to Characterize Histone Post-translational Modification (PTM) Combinatorics at Distinct Genomic Regions.

Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML.