Laboratory of Lymphocyte Biology
F. Nina Papavasiliou has not added Biography.
If you are F. Nina Papavasiliou and would like to personalize this page please email our Author Liaison for assistance.
Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity.
Cell Apr, 2002 | Pubmed ID: 11983151
The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process.
The Journal of experimental medicine May, 2002 | Pubmed ID: 11994424
A modified digestion-circularization PCR (DC-PCR) approach to detect hypermutation-associated DNA double-strand breaks.
Annals of the New York Academy of Sciences Apr, 2003 | Pubmed ID: 12727632
AID mediates hypermutation by deaminating single stranded DNA.
The Journal of experimental medicine May, 2003 | Pubmed ID: 12756266
V(D)J recombination and the evolution of the adaptive immune system.
PLoS biology Oct, 2003 | Pubmed ID: 14551913
The regulation of somatic hypermutation.
Current opinion in immunology Apr, 2004 | Pubmed ID: 15023419
The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination.
Molecular and cellular biology Jun, 2006 | Pubmed ID: 16705187
A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.
Immunity Jun, 2006 | Pubmed ID: 16782033
Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-kappaB.
The Journal of experimental medicine Feb, 2007 | Pubmed ID: 17242162
Regulation of AID expression in the immune response.
The Journal of experimental medicine May, 2007 | Pubmed ID: 17452520
An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA.
Proceedings of the National Academy of Sciences of the United States of America May, 2007 | Pubmed ID: 17483465
Beyond SHM and CSR: AID and related cytidine deaminases in the host response to viral infection.
Advances in immunology , 2007 | Pubmed ID: 17560276
Immunoglobulin somatic hypermutation.
Annual review of genetics , 2007 | Pubmed ID: 17576170
A mammalian microRNA expression atlas based on small RNA library sequencing.
Cell Jun, 2007 | Pubmed ID: 17604727
C to U editing at position 32 of the anticodon loop precedes tRNA 5' leader removal in trypanosomatids.
Nucleic acids research , 2007 | Pubmed ID: 17916576
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.
Immunity May, 2008 | Pubmed ID: 18450484
Shhh! Silencing by microRNA-155.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Mar, 2009 | Pubmed ID: 19008191
A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei.
Nature May, 2009 | Pubmed ID: 19369939
A coming-of-age story: activation-induced cytidine deaminase turns 10.
Nature immunology Nov, 2009 | Pubmed ID: 19841648
Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region.
The Journal of experimental medicine Nov, 2009 | Pubmed ID: 19887393
MicroRNAs of the immune system: roles in inflammation and cancer.
Annals of the New York Academy of Sciences Jan, 2010 | Pubmed ID: 20146715
Diverse functions for DNA and RNA editing in the immune system.
RNA biology Mar-Apr, 2010 | Pubmed ID: 20220309
Long noncoding RNAs: implications for antigen receptor diversification.
Advances in immunology , 2009 | Pubmed ID: 20457115
Using T. brucei as a biological epitope-display platform to elicit specific antibody responses.
Journal of immunological methods Oct, 2010 | Pubmed ID: 20800596
Cytidine deaminases: AIDing DNA demethylation?
Genes & development Oct, 2010 | Pubmed ID: 20889711
A role for autophagic protein beclin 1 early in lymphocyte development.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2011 | Pubmed ID: 21239722
Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3' UTRs.
Nature structural & molecular biology Feb, 2011 | Pubmed ID: 21258325
MicroRNA control of lymphocyte differentiation and function.
Current opinion in immunology Jun, 2011 | Pubmed ID: 21353514
Identifying mRNA editing deaminase targets by RNA-Seq.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21370044
A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase.
The Journal of biological chemistry Jun, 2011 | Pubmed ID: 21507956
The C-terminal end of the Trypanosoma brucei editing deaminase plays a critical role in tRNA binding.
RNA (New York, N.Y.) Jul, 2011 | Pubmed ID: 21602302
Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei.
PLoS pathogens , 2012 | Pubmed ID: 22952449
Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2013 | Pubmed ID: 23277564
A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells.
Nature immunology Jul, 2013 | Pubmed ID: 23708250
You break it, you fix it: functions for AID downstream of deamination.
Nature immunology Nov, 2013 | Pubmed ID: 24145783
The in vivo dynamics of antigenic variation in Trypanosoma brucei.
Science (New York, N.Y.) Mar, 2015 | Pubmed ID: 25814582
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
Cell reports Sep, 2015 | Pubmed ID: 26365193
A Host-Pathogen Interaction Reduced to First Principles: Antigenic Variation in T. brucei.
Results and problems in cell differentiation , 2015 | Pubmed ID: 26537376
Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome.
PLoS biology Dec, 2015 | Pubmed ID: 26646171
Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei.
PLoS genetics Jan, 2016 | Pubmed ID: 26796638
Epigenetic Modulators of Monocytic Function: Implication for Steady State and Disease in the CNS.
Frontiers in immunology , 2015 | Pubmed ID: 26834738
Pseudouridylation meets next-generation sequencing.
Methods (San Diego, Calif.) Sep, 2016 | Pubmed ID: 26968262
Vesicles as Vehicles for Virulence.
Trends in parasitology Jun, 2016 | Pubmed ID: 27006155
A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive.
PLoS genetics May, 2016 | Pubmed ID: 27149665
The VEXing problem of monoallelic expression in the African trypanosome.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2016 | Pubmed ID: 27317742
RNA editing generates cellular subsets with diverse sequence within populations.
Nature communications , 2016 | Pubmed ID: 27418407
Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei.
PLoS pathogens Sep, 2016 | Pubmed ID: 27583379
RNA Editing Dynamically Rewrites the Cancer Code.
Trends in cancer Dec, 2015 | Pubmed ID: 27695712
JoVE Hakkında
Telif Hakkı © 2020 MyJove Corporation. Tüm hakları saklıdır