John Roder

Place-cell impairment in glutamate receptor 2 mutant mice.

Sweeping model of dynamin activity. Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins.

Increased drinking in mutant mice with truncated M5 muscarinic receptor genes.

Neuronal calcium sensor 1 and activity-dependent facilitation of P/Q-type calcium currents at presynaptic nerve terminals.

Alterations in exocytosis induced by neuronal Ca2+ sensor-1 in bovine chromaffin cells.

Neuronal calcium sensor-1 binds to regulated secretory organelles and functions in basal and stimulated exocytosis in PC12 cells.

Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells.

AMPA receptor-mediated miniature synaptic calcium transients in GluR2 null mice.

Differential expression of neuronal calcium sensor-1 in the developing chick retina.

Non-ionotropic cross-talk between AMPA and NMDA receptors in rodent hippocampal neurones.

Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase beta interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis.

Compartmentation of the mouse cerebellar cortex by neuronal calcium sensor-1.

Aging effects on spatial tuning of hippocampal place cells in mice.

Spatiotemporal distribution of neuronal calcium sensor-1 in the developing rat spinal cord.

Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons.

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.

Visualization of vesicle transport along and between distinct pathways in neurites of living cells.

Identification and subcellular localization of neuronal calcium sensor-1 (NCS-1) in human neutrophils and HL-60 cells.

N-terminal myristoylation regulates calcium-induced conformational changes in neuronal calcium sensor-1.

Survey of embryonic stem cell line source strains in the water maze reveals superior reversal learning of 129S6/SvEvTac mice.

Calcium and chlorpromazine binding to the EF-hand peptides of neuronal calcium sensor-1.

The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Neuronal calcium sensor-1 facilitates neuronal exocytosis through phosphatidylinositol 4-kinase.

Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia.

Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation.

Simplex PCR assay for sex determination in mice.

NIH Swiss and Black Swiss mice have retinal degeneration and performance deficits in cognitive tests.

Effects of the rd1 mutation and host strain on hippocampal learning in mice.

Novel strategies for the development of animal models of refractory epilepsy.

Impairment in long-term retention but not short-term performance on a water maze reversal task following hippocampal or mediodorsal striatal N-methyl-D-aspartate receptor blockade.

Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.

In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice.

Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function.

Methods to rapidly and accurately screen a large number of ENU mutagenized mice for abnormal motor phenotypes.

Psychosis pathways converge via D2high dopamine receptors.

The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice.

Recent advances in basic neurosciences and brain disease: from synapses to behavior.

NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.

Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice.

Behavioral phenotypes of Disc1 missense mutations in mice.

D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning.

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.

Neuronal calcium sensor-1 modulation of optimal calcium level for neurite outgrowth.

Nck adaptor proteins control the organization of neuronal circuits important for walking.

ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1.

Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.

Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors.

Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice.

Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

beta-adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cells.

Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.

Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.

The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia.

NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory.

Abnormalities in brain structure and behavior in GSK-3alpha mutant mice.

A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment.

Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory.

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.

Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice.

Determination of L-serine-O-phosphate in rat and mouse brain tissue using high-performance liquid chromatography and fluorimetric detection.

Src inhibition reduces NR2B surface expression and synaptic plasticity in the amygdala.

Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.

A new Kv1.2 channelopathy underlying cerebellar ataxia.

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.

Short-term memory impairment after isoflurane in mice is prevented by the α5 γ-aminobutyric acid type A receptor inverse agonist L-655,708.

Contributions of the d-serine pathway to schizophrenia.

Disc1 point mutations in mice affect development of the cerebral cortex.

Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice.

N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination.

Statistical and theoretical considerations for the platform re-location water maze.

A co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channel.

Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice.

Missense mutation of the reticulon-4 receptor alters spatial memory and social interaction in mice.

Memantine affects cognitive flexibility in the morris water maze.

Parametric and pharmacological modulations of latent inhibition in mouse inbred strains.

Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump.

Acute pharmacokinetics of memantine in the mouse.

Paradoxical roles of serine racemase and d-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis.

Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction.