Samuel Lunenfeld Research Institute
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Place-cell impairment in glutamate receptor 2 mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2002 | Pubmed ID: 11826150
Sweeping model of dynamin activity. Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins.
The Journal of biological chemistry May, 2002 | Pubmed ID: 11856729
Increased drinking in mutant mice with truncated M5 muscarinic receptor genes.
Pharmacology, biochemistry, and behavior May, 2002 | Pubmed ID: 11900778
Neuronal calcium sensor 1 and activity-dependent facilitation of P/Q-type calcium currents at presynaptic nerve terminals.
Science (New York, N.Y.) Mar, 2002 | Pubmed ID: 11910115
Alterations in exocytosis induced by neuronal Ca2+ sensor-1 in bovine chromaffin cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2002 | Pubmed ID: 11923406
Neuronal calcium sensor-1 binds to regulated secretory organelles and functions in basal and stimulated exocytosis in PC12 cells.
Journal of cell science Jun, 2002 | Pubmed ID: 12006624
Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12034721
AMPA receptor-mediated miniature synaptic calcium transients in GluR2 null mice.
Journal of neurophysiology Jul, 2002 | Pubmed ID: 12091530
Differential expression of neuronal calcium sensor-1 in the developing chick retina.
The Journal of comparative neurology Jul, 2002 | Pubmed ID: 12115677
Non-ionotropic cross-talk between AMPA and NMDA receptors in rodent hippocampal neurones.
The Journal of physiology Aug, 2002 | Pubmed ID: 12181279
Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase beta interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis.
Journal of cell science Oct, 2002 | Pubmed ID: 12244129
Compartmentation of the mouse cerebellar cortex by neuronal calcium sensor-1.
The Journal of comparative neurology Apr, 2003 | Pubmed ID: 12619075
Aging effects on spatial tuning of hippocampal place cells in mice.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale May, 2003 | Pubmed ID: 12677315
Spatiotemporal distribution of neuronal calcium sensor-1 in the developing rat spinal cord.
The Journal of comparative neurology Jun, 2003 | Pubmed ID: 12717707
Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons.
The Journal of biological chemistry Jul, 2003 | Pubmed ID: 12740378
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.
The EMBO journal Jul, 2003 | Pubmed ID: 12839988
Visualization of vesicle transport along and between distinct pathways in neurites of living cells.
Microscopy research and technique Feb, 2004 | Pubmed ID: 14755603
Identification and subcellular localization of neuronal calcium sensor-1 (NCS-1) in human neutrophils and HL-60 cells.
Inflammation Dec, 2003 | Pubmed ID: 14760944
N-terminal myristoylation regulates calcium-induced conformational changes in neuronal calcium sensor-1.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15102861
Survey of embryonic stem cell line source strains in the water maze reveals superior reversal learning of 129S6/SvEvTac mice.
Behavioural brain research Jun, 2004 | Pubmed ID: 15135967
Calcium and chlorpromazine binding to the EF-hand peptides of neuronal calcium sensor-1.
Peptides Jun, 2004 | Pubmed ID: 15203236
The Collaborative Cross, a community resource for the genetic analysis of complex traits.
Nature genetics Nov, 2004 | Pubmed ID: 15514660
Neuronal calcium sensor-1 facilitates neuronal exocytosis through phosphatidylinositol 4-kinase.
Journal of neurochemistry Feb, 2005 | Pubmed ID: 15659215
Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia.
Psychopharmacology Apr, 2005 | Pubmed ID: 15759151
Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation.
The Journal of physiology Jun, 2005 | Pubmed ID: 15774528
Simplex PCR assay for sex determination in mice.
BioTechniques May, 2005 | Pubmed ID: 15945368
NIH Swiss and Black Swiss mice have retinal degeneration and performance deficits in cognitive tests.
Comparative medicine Aug, 2005 | Pubmed ID: 16158906
Effects of the rd1 mutation and host strain on hippocampal learning in mice.
Behavior genetics Sep, 2005 | Pubmed ID: 16184487
Novel strategies for the development of animal models of refractory epilepsy.
Advances in neurology , 2006 | Pubmed ID: 16383125
Impairment in long-term retention but not short-term performance on a water maze reversal task following hippocampal or mediodorsal striatal N-methyl-D-aspartate receptor blockade.
Behavioral neuroscience Dec, 2005 | Pubmed ID: 16420159
Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2006 | Pubmed ID: 16597725
In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2006 | Pubmed ID: 16641223
Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function.
Genetics Aug, 2006 | Pubmed ID: 16751659
Methods to rapidly and accurately screen a large number of ENU mutagenized mice for abnormal motor phenotypes.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases Jun, 2006 | Pubmed ID: 16753976
Psychosis pathways converge via D2high dopamine receptors.
Synapse (New York, N.Y.) Sep, 2006 | Pubmed ID: 16786561
The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Apr, 2007 | Pubmed ID: 16936708
Recent advances in basic neurosciences and brain disease: from synapses to behavior.
Molecular pain , 2006 | Pubmed ID: 17196111
NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2007 | Pubmed ID: 17329427
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17360389
Behavioral phenotypes of Disc1 missense mutations in mice.
Neuron May, 2007 | Pubmed ID: 17481393
D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Apr, 2008 | Pubmed ID: 17625504
Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.
The Journal of physiology Oct, 2007 | Pubmed ID: 17823207
Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2007 | Pubmed ID: 17928447
Neuronal calcium sensor-1 modulation of optimal calcium level for neurite outgrowth.
Development (Cambridge, England) Dec, 2007 | Pubmed ID: 18039973
Nck adaptor proteins control the organization of neuronal circuits important for walking.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18093944
ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1.
Traffic (Copenhagen, Denmark) May, 2008 | Pubmed ID: 18298590
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.
Psychopharmacology Oct, 2008 | Pubmed ID: 18597079
Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors.
Pharmacology, biochemistry, and behavior Feb, 2009 | Pubmed ID: 18940194
Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice.
Learning & memory (Cold Spring Harbor, N.Y.) Jan, 2009 | Pubmed ID: 19117914
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.
PLoS biology Feb, 2009 | Pubmed ID: 19243221
beta-adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cells.
American journal of physiology. Heart and circulatory physiology Jun, 2009 | Pubmed ID: 19395557
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.
Human molecular genetics Sep, 2009 | Pubmed ID: 19483194
Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19666602
The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia.
Neuroscience and biobehavioral reviews Mar, 2010 | Pubmed ID: 19695284
NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory.
Neuron Sep, 2009 | Pubmed ID: 19755107
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice.
Molecular brain , 2009 | Pubmed ID: 19925672
A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment.
Psychopharmacology Feb, 2010 | Pubmed ID: 20013111
Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2010 | Pubmed ID: 20392949
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.
Human molecular genetics Jul, 2010 | Pubmed ID: 20442137
Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice.
Mammalian genome : official journal of the International Mammalian Genome Society Jun, 2010 | Pubmed ID: 20512340
Determination of L-serine-O-phosphate in rat and mouse brain tissue using high-performance liquid chromatography and fluorimetric detection.
Analytical biochemistry Oct, 2010 | Pubmed ID: 20599655
Src inhibition reduces NR2B surface expression and synaptic plasticity in the amygdala.
Learning & memory (Cold Spring Harbor, N.Y.) Aug, 2010 | Pubmed ID: 20660101
Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.
Synapse (New York, N.Y.) Mar, 2011 | Pubmed ID: 20687111
A new Kv1.2 channelopathy underlying cerebellar ataxia.
The Journal of biological chemistry Oct, 2010 | Pubmed ID: 20696761
Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.
Brain research Dec, 2010 | Pubmed ID: 20932954
Short-term memory impairment after isoflurane in mice is prevented by the α5 γ-aminobutyric acid type A receptor inverse agonist L-655,708.
Anesthesiology Nov, 2010 | Pubmed ID: 20966663
Contributions of the d-serine pathway to schizophrenia.
Neuropharmacology Mar, 2012 | Pubmed ID: 21295046
Disc1 point mutations in mice affect development of the cerebral cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2011 | Pubmed ID: 21368031
Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice.
Neuropharmacology Mar, 2012 | Pubmed ID: 21376063
N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination.
Development (Cambridge, England) Apr, 2011 | Pubmed ID: 21385763
Statistical and theoretical considerations for the platform re-location water maze.
Journal of neuroscience methods May, 2011 | Pubmed ID: 21419797
A co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channel.
Molecular brain , 2011 | Pubmed ID: 21489288
Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice.
Schizophrenia research Jun, 2011 | Pubmed ID: 21498050
Missense mutation of the reticulon-4 receptor alters spatial memory and social interaction in mice.
Behavioural brain research Oct, 2011 | Pubmed ID: 21645550
Memantine affects cognitive flexibility in the morris water maze.
Journal of Alzheimer's disease : JAD , 2011 | Pubmed ID: 21860092
Parametric and pharmacological modulations of latent inhibition in mouse inbred strains.
Pharmacology, biochemistry, and behavior Dec, 2011 | Pubmed ID: 21903127
Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22025725
Acute pharmacokinetics of memantine in the mouse.
Pharmacology , 2011 | Pubmed ID: 22068149
Paradoxical roles of serine racemase and d-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis.
Journal of neurochemistry Feb, 2012 | Pubmed ID: 22117694
Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction.
Behavioural brain research Feb, 2012 | Pubmed ID: 22326373
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