Robert Rieben

Successful management of an ABO-mismatched lung allograft using antigen-specific immunoadsorption, complement inhibition, and immunomodulatory therapy.

C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction.

Activation of complement pathways in xenotransplantation: an in vitro study.

P-selectin blocking potency of multimeric tyrosine sulfates in vitro and in vivo.

Dextran sulfate acts as an endothelial cell protectant and inhibits human complement and natural killer cell-mediated cytotoxicity against porcine cells.

IgM-enriched human introvenous immunoglobulin strongly inhibits complement-dependent porcine cell cytotoxicity mediated by human xenoreactive antibodies.

Immunoglobulin M-enriched intravenous immunoglobulin inhibits classical pathway complement activation, but not bactericidal activity of human serum.

Endothelial cell protection by dextran sulfate: a novel strategy to prevent acute vascular rejection in xenotransplantation.

Multimeric tyrosine sulfate acts as an endothelial cell protectant and prevents complement activation in xenotransplantation models.

Lack of galactose-alpha-1,3-galactose expression on porcine endothelial cells prevents complement-induced lysis but not direct xenogeneic NK cytotoxicity.

Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium.

Histo-blood group antigens as allo- and autoantigens.

Locally targeted cytoprotection with dextran sulfate attenuates experimental porcine myocardial ischaemia/reperfusion injury.

Endothelial cell protection and complement inhibition in xenotransplantation: a novel in vitro model using whole blood.

Endothelial cell protection in xenotransplantation: looking after a key player in rejection.

Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs.

AB0 blood group incompatible haematopoietic stem cell transplantation and xenograft rejection.

Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1.

ABO blood group incompatible haematopoietic stem cell transplantation and xenograft rejection.

Normal human serum contains high levels of anti-Gal alpha 1-4GlcNAc antibodies.

Addition of dextran sulfate to blood cardioplegia attenuates reperfusion injury in a porcine model of cardiopulmonary bypass.

The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells.

Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation.

TLR2 and TLR4 agonists induce production of the vasoactive peptide endothelin-1 by human dendritic cells.

Dextran sulfate modulates MAP kinase signaling and reduces endothelial injury in a rat aortic clamping model.

Exploring natural anticoagulation by endothelial cells: a novel in vitro model.

Preservation of amputated extremities by extracorporeal blood perfusion; a feasibility study in a porcine model.

Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions.

Inhibition of direct and indirect TLR-mediated activation of human NK cells by low molecular weight dextran sulfate.

Multiplex suspension array for human anti-carbohydrate antibody profiling.

Role of complement and perspectives for intervention in ischemia-reperfusion damage.

Autotransfusion system or integrated automatic suction device in minimized extracorporeal circulation: influence on coagulation and inflammatory response.

Evaluation of multimeric tyrosine-O-sulfate as a cytoprotectant in an in vivo model of acute myocardial infarction in pigs.

Pancuronium dose refinement in experimental pigs used in cardiovascular research.

Assessment of endothelium and inflammatory response at the onset of reperfusion injury in hand surgery.

Ischemia/reperfusion injury of porcine limbs after extracorporeal perfusion.

Microsurgery and liver research: Lumbricus terrestris, a reliable animal model for training?

Development of a bead-based multiplex assay for the simultaneous detection of porcine inflammation markers using xMAP technology.

Botulinum toxin A and B raise blood flow and increase survival of critically ischemic skin flaps.

Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis.

Edema is a sign of early acute myocardial infarction on post-mortem magnetic resonance imaging.

Effect of pressure-controlled intermittent coronary sinus occlusion (PICSO) on myocardial ischaemia and reperfusion in a closed-chest porcine model.

Activation of the lectin pathway of complement in pig-to-human xenotransplantation models.

Reconstituted high-density lipoprotein modulates activation of human leukocytes.

C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage.

Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.

Use of dextran sulfate in tourniquet-induced skeletal muscle reperfusion injury.

Ischemia/reperfusion injury: effect of simultaneous inhibition of plasma cascade systems versus specific complement inhibition.

Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

A single localized dose of enzyme-responsive hydrogel improves long-term survival of a vascularized composite allograft.

Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion.

Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14.

Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions.

Endothelial- and Platelet-Derived Microparticles Are Generated During Liver Resection in Humans.

Modifying the Glycome in Pigs for Xenotransplantation.

Higher macrophage superoxide anion production in coronary artery disease (CAD) patients with Type D personality.

Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation.

Correlation Between Sonographic and In Vivo Measurement of A1 Pulleys in Trigger Fingers.

Vitreal Cytokine Profile Differences Between Eyes With Epiretinal Membranes or Macular Holes.

Dexrazoxane Shows No Protective Effect in the Acute Phase of Reperfusion during Myocardial Infarction in Pigs.

Role of the plasma cascade systems in ischemia/reperfusion injury of bone.

Xenotransplantation: Where do we stand in 2016?

Effect of C1-INH on ischemia/reperfusion injury in a porcine limb ex vivo perfusion model.

Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood.

Bioengineering a Human Face Graft: The Matrix of Identity.

Intra-graft injection of tacrolimus promotes survival of vascularized composite allotransplantation.

Release of pig leukocytes and reduced human NK cell recruitment during ex vivo perfusion of HLA-E/human CD46 double-transgenic pig limbs with human blood.

Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model.

Type II Minimal-Invasive Extracorporeal Circuit for Aortic Valve Replacement: A Randomized Controlled Trial.