Department of Molecular Genetics
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Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.
Nature 05, 2021 | Pubmed ID: 33731940
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.
Nature Aug, 2012 | Pubmed ID: 22801502
Oct4 shuffles Sox partners to direct cell fate.
The EMBO journal Apr, 2013 | Pubmed ID: 23474893
The expression of the beta cell-derived autoimmune ligand for the killer receptor nkp46 is attenuated in type 2 diabetes.
PloS one , 2013 | Pubmed ID: 24009765
Deterministic direct reprogramming of somatic cells to pluripotency.
Nature Oct, 2013 | Pubmed ID: 24048479
Derivation of novel human ground state naive pluripotent stem cells.
Nature Dec, 2013 | Pubmed ID: 24172903
Passage number is a major contributor to genomic structural variations in mouse iPSCs.
Stem cells (Dayton, Ohio) Oct, 2014 | Pubmed ID: 24965231
Lucky iPSCs.
Genome biology Mar, 2014 | Pubmed ID: 25002192
Stem cells: The quest for the perfect reprogrammed cell.
Nature Jul, 2014 | Pubmed ID: 25008516
Hijacked by an oocyte: hierarchical molecular changes in somatic cell nuclear transfer.
Molecular cell Aug, 2014 | Pubmed ID: 25148360
SOX17 is a critical specifier of human primordial germ cell fate.
Cell Jan, 2015 | Pubmed ID: 25543152
Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.
Science (New York, N.Y.) Feb, 2015 | Pubmed ID: 25569111
CD24 tracks divergent pluripotent states in mouse and human cells.
Nature communications Jun, 2015 | Pubmed ID: 26076835
Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors.
Nature biotechnology Jul, 2015 | Pubmed ID: 26098448
Establishing the human naïve pluripotent state.
Current opinion in genetics & development Oct, 2015 | Pubmed ID: 26291026
Failure to replicate the STAP cell phenomenon.
Nature Sep, 2015 | Pubmed ID: 26399835
An essential role for UTX in resolution and activation of bivalent promoters.
Nucleic acids research 05, 2016 | Pubmed ID: 26762983
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs.
Genome biology Feb, 2016 | Pubmed ID: 26838501
Dynamic stem cell states: naive to primed pluripotency in rodents and humans.
Nature reviews. Molecular cell biology Mar, 2016 | Pubmed ID: 26860365
Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution.
Nature biotechnology 09, 2016 | Pubmed ID: 27454738
Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Nature immunology 02, 2017 | Pubmed ID: 27941786
mA mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
Genes & development 05, 2017 | Pubmed ID: 28637692
A multiplexed screening method for pluripotency.
Stem cell research 08, 2017 | Pubmed ID: 28756340
Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression.
Scientific reports 10, 2017 | Pubmed ID: 29026144
OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs.
Nature communications Oct, 2017 | Pubmed ID: 29044103
Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs.
Proceedings of the National Academy of Sciences of the United States of America 11, 2017 | Pubmed ID: 29087313
NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis.
Immunity 01, 2018 | Pubmed ID: 29329948
RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells.
Stem cell reports 03, 2018 | Pubmed ID: 29456180
mA deposition: a boost from TGFβ.
Cell research May, 2018 | Pubmed ID: 29679051
Human Brain Organoids on a Chip Reveal the Physics of Folding.
Nature physics May, 2018 | Pubmed ID: 29760764
Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies.
Immunity May, 2018 | Pubmed ID: 29768178
The Role of mA/m-RNA Methylation in Stress Response Regulation.
Neuron Jul, 2018 | Pubmed ID: 30048615
Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.
Cell stem cell Sep, 2018 | Pubmed ID: 30122475
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells.
Nature communications 12, 2018 | Pubmed ID: 30510213
Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.
Cell stem cell Dec, 2018 | Pubmed ID: 30554962
mA modification controls the innate immune response to infection by targeting type I interferons.
Nature immunology 02, 2019 | Pubmed ID: 30559377
The N-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.
Circulation 01, 2019 | Pubmed ID: 30586742
Publisher Correction: m6A modification controls the innate immune response to infection by targeting type I interferons.
Nature immunology 02, 2019 | Pubmed ID: 30635652
Stem Cell-Derived Human Gametes: The Public Engagement Imperative.
Trends in molecular medicine 03, 2019 | Pubmed ID: 30738627
Universally non-immunogenic iPSCs.
Nature biomedical engineering 05, 2019 | Pubmed ID: 31036889
Stage-specific requirement for Mettl3-dependent mA mRNA methylation during haematopoietic stem cell differentiation.
Nature cell biology 06, 2019 | Pubmed ID: 31061465
Deciphering the "mA Code" via Antibody-Independent Quantitative Profiling.
Cell 07, 2019 | Pubmed ID: 31257032
Generation of human endothelium in pig embryos deficient in ETV2.
Nature biotechnology 03, 2020 | Pubmed ID: 32094659
β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus.
Science advances Jul, 2020 | Pubmed ID: 32832621
Production and Analysis of Human Primordial Germ Cell-Like Cells.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 32852762
Context-dependent functional compensation between Ythdf mA reader proteins.
Genes & development 10, 2020 | Pubmed ID: 32943573
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Molecular cell 12, 2020 | Pubmed ID: 33217318
Principles of signaling pathway modulation for enhancing human naive pluripotency induction.
Cell stem cell 09, 2021 | Pubmed ID: 33915080
Modeling genetic epileptic encephalopathies using brain organoids.
EMBO molecular medicine Aug, 2021 | Pubmed ID: 34268881
The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers.
The Journal of experimental medicine Oct, 2021 | Pubmed ID: 34402854
Mechanism of noncoding RNA-associated N-methyladenosine recognition by an RNA processing complex during IgH DNA recombination.
Molecular cell Oct, 2021 | Pubmed ID: 34450044
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