Xu Li
State Key Laboratory of Bioelectronics,
School of Biological Science & Medical Engineering,
State Key Laboratory of Bioelectronics, School of Biological Science & Medical Engineering
Southeast University
Xue-Jun Li received her PhD in Neurobiology from Shanghai Medical College of Fudan University in 2000. To pursue her strong interests in neurodegenerative disease and regenerative medicine, she joined the Stem Cell Research Program at the University of Wisconsin-Madison, first as a postdoctoral associate and then as an assistant scientist. In 2007, she joined the Neuroscience Department at the University of Connecticut Health Center as an assistant professor. She is also a PI of the University of Connecticut Stem Cell Institute. In February 2016, Dr. Li joined the Department of Biomedical Sciences at the College of Medicine-Rockford and the Department of Bioengineering at the University of Illinois-Chicago as an associate professor. Dr. Li's research focuses on specifying neuronal subtypes from human pluripotent stem cells (hPSCs including both human embryonic stem cells and induced pluripotent stem cells) and using these stem cell-derived neurons to study motor neuron and axonal degeneration. Dr. Li has published over 40 peer reviewed manuscripts and 3 book chapters. As the lead author, she published the seminal report on the specification of spinal motor neurons from hPSCs (Nature Biotechnology, 2005). This paradigm she developed has been widely used in motor neuron research (>800 citations; Google Scholar 01/2020). Recently, her lab has successfully established human stem cell models for spinal muscular atrophy (Cell Research, 2013; Disease Models & Mechanisms, 2016) and hereditary spastic paraplegias (Stem Cells, 2014; Human Molecular Genetics, 2014 & 2018). Her research is supported by grant funding from the National Institute of Health, the Spastic Paraplegia Foundation, the Blazer Foundation, the Connecticut Stem Cell Research Program and the ALS Association. By combining cellular, molecular, bioengineering and system approaches, research in her lab aims to understand the pathogenic mechanisms of motor neuron diseases and to develop therapeutics for the treatment of these debilitating diseases.
Three-dimensional noninvasive ultrasound Joule heat tomography based on the acousto-electric effect using unipolar pulses: a simulation study.
Physics in medicine and biology Nov, 2012 | Pubmed ID: 23123757
A 3-D reconstruction solution to current density imaging based on acoustoelectric effect by deconvolution: a simulation study.
IEEE transactions on bio-medical engineering May, 2013 | Pubmed ID: 23192473
A hybrid positioning strategy for vehicles in a tunnel based on RFID and in-vehicle sensors.
Sensors (Basel, Switzerland) Dec, 2014 | Pubmed ID: 25490581
Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice.
Nature communications Jan, 2015 | Pubmed ID: 25565658
High Rab27A expression indicates favorable prognosis in CRC.
Diagnostic pathology , 2015 | Pubmed ID: 26070933
Antifouling coatings based on covalently cross-linked agarose film via thermal azide-alkyne cycloaddition.
Colloids and surfaces. B, Biointerfaces May, 2016 | Pubmed ID: 26836479
A Highly Reliable and Cost-Efficient Multi-Sensor System for Land Vehicle Positioning.
Sensors (Basel, Switzerland) May, 2016 | Pubmed ID: 27231917
Sum Frequency Generation of Interfacial Lipid Monolayers Shows Polarization Dependence on Experimental Geometries.
Langmuir : the ACS journal of surfaces and colloids 07, 2016 | Pubmed ID: 27364607
Self-Assembled Exopolysaccharide Nanoparticles for Bioremediation and Green Synthesis of Noble Metal Nanoparticles.
ACS applied materials & interfaces Jul, 2017 | Pubmed ID: 28613815
A Cost-Effective Vehicle Localization Solution Using an Interacting Multiple Model-Unscented Kalman Filters (IMM-UKF) Algorithm and Grey Neural Network.
Sensors (Basel, Switzerland) Jun, 2017 | Pubmed ID: 28629165
Calcium-dependent hydrolysis of supported planar lipids was triggered by honey bee venom phospholipase A with the right orientation at the interface.
Physical chemistry chemical physics : PCCP Dec, 2017 | Pubmed ID: 29149234
Observing different dynamic behaviors of weakly and strongly adsorbed polystyrene chains at interfaces.
Soft matter Apr, 2018 | Pubmed ID: 29441390
Interchain Overlap Affects Formation of Silk Fibroin Secondary Structures on Hydrophobic Polystyrene Surface Detected via Achiral/Chiral Sum Frequency Generation.
Langmuir : the ACS journal of surfaces and colloids 08, 2018 | Pubmed ID: 29983068
Calcium Ions Affect Water Molecular Structures Surrounding an Oligonucleotide Duplex as Revealed by Sum Frequency Generation Vibrational Spectroscopy.
Langmuir : the ACS journal of surfaces and colloids 12, 2018 | Pubmed ID: 30089212
Molecular Coupling between Organic Molecules and Metal.
The journal of physical chemistry letters Sep, 2018 | Pubmed ID: 30141630
Sum Frequency Generation Vibrational Spectroscopy Using Evanescent Waves-Toward Probing Irregular and Complex Surfaces of Mesoscopic-Scale Materials.
Analytical chemistry 12, 2018 | Pubmed ID: 30444354
A temperature-triggered triplex bistable switch in a hybrid multifunctional material: [(CH)N(CH)][MnBr].
Dalton transactions (Cambridge, England : 2003) Dec, 2018 | Pubmed ID: 30460952
Black Currant Anthocyanins Attenuate Weight Gain and Improve Glucose Metabolism in Diet-Induced Obese Mice with Intact, but Not Disrupted, Gut Microbiome.
Journal of agricultural and food chemistry Jul, 2015 | Pubmed ID: 26066489
Discovery of a novel amino acid racemase through exploration of natural variation in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2015 | Pubmed ID: 26324904
Maize Homologs of Hydroxycinnamoyltransferase, a Key Enzyme in Lignin Biosynthesis, Bind the Nucleotide Binding Leucine-Rich Repeat Rp1 Proteins to Modulate the Defense Response.
Plant physiology Nov, 2015 | Pubmed ID: 26373661
Landscape position influences microbial composition and function via redistribution of soil water across a watershed.
Applied and environmental microbiology Dec, 2015 | Pubmed ID: 26431971
Identification of a residue responsible for UDP-sugar donor selectivity of a dihydroxybenzoic acid glycosyltransferase from Arabidopsis natural accessions.
The Plant journal : for cell and molecular biology Jan, 2017 | Pubmed ID: 27411741
A gene encoding maize caffeoyl-CoA O-methyltransferase confers quantitative resistance to multiple pathogens.
Nature genetics Sep, 2017 | Pubmed ID: 28740263
Comprehensive transcriptome analyses correlated with untargeted metabolome reveal differentially expressed pathways in response to cell wall alterations.
Plant molecular biology Mar, 2018 | Pubmed ID: 29502299
Discovering variation of secondary metabolite diversity and its relationship with disease resistance in L.
Ecology and evolution Jun, 2018 | Pubmed ID: 29938079
Overcoming cellulose recalcitrance in woody biomass for the lignin-first biorefinery.
Biotechnology for biofuels , 2019 | Pubmed ID: 31297159
NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.
Molecular & cellular proteomics : MCP Jan, 2020 | Pubmed ID: 31591262
Investigation of the microplastics profile in sludge from China's largest Water reclamation plant using a feasible isolation device.
Journal of hazardous materials Apr, 2020 | Pubmed ID: 31951991
An importin-beta-like protein mediates lignin-modification-induced dwarfism in Arabidopsis.
The Plant journal : for cell and molecular biology Jun, 2020 | Pubmed ID: 31972869
An Efficient Stevia rebaudiana Transformation System and In vitro Enzyme Assays Reveal Novel Insights into UGT76G1 Function.
Scientific reports Feb, 2020 | Pubmed ID: 32111874
Aggregation of Polybismuthide Anions in a Single Compound Using Rh-CO Units: Heterometallic Cluster Ions [Rh@Bi(RhCO)] and [Rh@Bi(RhCO)].
Inorganic chemistry Aug, 2020 | Pubmed ID: 32673479
Combination of plant-growth-promoting and fluoranthene-degrading microbes enhances phytoremediation efficiency in the ryegrass rhizosphere.
Environmental science and pollution research international Feb, 2021 | Pubmed ID: 32989700
Metabolic source isotopic pair labeling and genome-wide association are complementary tools for the identification of metabolite-gene associations in plants.
The Plant cell May, 2021 | Pubmed ID: 33955498
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