Hairuo Lin
Department of Cardiology,
State Key Laboratory of Organ Failure Research,
Nanfang Hospital,
Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital
Southern Medical University
Hairuo Lin is a graduate student in Cardiovascular Medicine at Southern Hospital of Southern Medical University. During his postgraduate studies, he mastered and improved a variety of mouse cardiovascular disease models, such as myocardial infarction (MI), aortic arch constriction (TAC), pulmonary trunk constriction (PAC) and left ventricular remodeling (LVR). He has been engaged in the research of cardiovascular disease pathogenesis, mainly focusing on the study of cardiac hypertrophy and heart failure. His current research direction is the involvement of non-coding RNAs in exercise hypertrophy preconditioning.
In his work, he used next-generation sequencing, CHIRP to analyze non-coding RNA and protein interactions in hypertrophic preconditioning mechanisms. At the same time, he first prepared and improved the PAC model in the laboratory to provide a stable animal model basis for the study of right heart hypertrophy.
HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload.
PloS one , 2016 | Pubmed ID: 27355349
FGF23 promotes myocardial fibrosis in mice through activation of β-catenin.
Oncotarget Oct, 2016 | Pubmed ID: 27579618
Acute hyperglycemia suppresses left ventricular diastolic function and inhibits autophagic flux in mice under prohypertrophic stimulation.
Cardiovascular diabetology Sep, 2016 | Pubmed ID: 27659110
Ablation of periostin inhibits post-infarction myocardial regeneration in neonatal mice mediated by the phosphatidylinositol 3 kinase/glycogen synthase kinase 3β/cyclin D1 signalling pathway.
Cardiovascular research May, 2017 | Pubmed ID: 28453729
Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin.
Cardiovascular research Jan, 2019 | Pubmed ID: 30689763
HIMF (Hypoxia-Induced Mitogenic Factor)-IL (Interleukin)-6 Signaling Mediates Cardiomyocyte-Fibroblast Crosstalk to Promote Cardiac Hypertrophy and Fibrosis.
Hypertension (Dallas, Tex. : 1979) May, 2019 | Pubmed ID: 30827145
Overexpression of Na-HCO cotransporter contributes to the exacerbation of cardiac remodeling in mice with myocardial infarction by increasing intracellular calcium overload.
Biochimica et biophysica acta. Molecular basis of disease 03, 2020 | Pubmed ID: 31778748
Bibliometric Study of Sodium Glucose Cotransporter 2 Inhibitors in Cardiovascular Research.
Frontiers in pharmacology , 2020 | Pubmed ID: 33041801
Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome.
Aging 01, 2021 | Pubmed ID: 33460402
RNA interactions in right ventricular dysfunction induced type II cardiorenal syndrome.
Aging 01, 2021 | Pubmed ID: 33494070
Antihypertrophic Memory After Regression of Exercise-Induced Physiological Myocardial Hypertrophy Is Mediated by the Long Noncoding RNA Mhrt779.
Circulation 06, 2021 | Pubmed ID: 33757294
Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling.
Aging 04, 2021 | Pubmed ID: 33891565
Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity.
Cell death & disease 07, 2021 | Pubmed ID: 34215721
Response by He et al to Letter Regarding Article, "Antihypertrophic Memory After Regression of Exercise-Induced Physiological Myocardial Hypertrophy Is Mediated by the Long Noncoding RNA Mhrt779".
Circulation 10, 2021 | Pubmed ID: 34662156
A Modified Surgical Ventricular Reconstruction in Post-infarction Mice Persistently Alleviates Heart Failure and Improves Cardiac Regeneration.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 35004900
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