Boris Lenhard

Making enhancers from spare parts of the genome.

Metazoan promoters: emerging characteristics and insights into transcriptional regulation.

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.

OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica.

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions.

r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data.

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments.

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles.

The mystery of extreme non-coding conservation.

Two independent transcription initiation codes overlap on vertebrate core promoters.

Computational characterization of modes of transcriptional regulation of nuclear receptor genes.

HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers.

Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest.

CAGEr: precise TSS data retrieval and high-resolution promoterome mining for integrative analyses.

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin.

Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome.

Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene.

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles.

GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data.

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs.

Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.

Promoter architectures and developmental gene regulation.

TFBSTools: an R/bioconductor package for transcription factor binding site analysis.

Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA-dependent Pre-transfer Editing.

Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation.

Core promoters across the genome.

Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation.

Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells.

Conserved non-coding elements: developmental gene regulation meets genome organization.

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework.

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework.

Distinct core promoter codes drive transcription initiation at key developmental transitions in a marine chordate.

Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte.

Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome.

BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells.

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.

SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA.

Amphioxus functional genomics and the origins of vertebrate gene regulation.

A Novel Measure of Non-coding Genome Conservation Identifies Genomic Regulatory Blocks Within Primates.

Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions.

DNA stretching induces Cas9 off-target activity.

Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.

Computation Resources for Molecular Biology: Special Issue 2019.