Boris Lenhard

Institute of Clinical Sciences, Imperial College London

Affiliated withImperial College London MRC London Institute of Medical Sciences University of Bergen

Research Area

Genetics

Biography

Boris Lenhard has not added Biography.
If you are Boris Lenhard and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2019

Other Publications

Article	Year
Making enhancers from spare parts of the genome. Genome biology\| PubMed ID: 22206586	2011
Metazoan promoters: emerging characteristics and insights into transcriptional regulation. Nature reviews. Genetics\| PubMed ID: 22392219	2012
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22451944	2012
A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Molecular and cellular biology\| PubMed ID: 22801375	2012
OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica. Nucleic acids research\| PubMed ID: 23185044	2013
Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions. Genome research\| PubMed ID: 23482648	2013
r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data. Nucleic acids research\| PubMed ID: 23671339	2013
Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments. Genome research\| PubMed ID: 24002784	2013
JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic acids research\| PubMed ID: 24194598	2014
The mystery of extreme non-coding conservation. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 24218634	2013
Two independent transcription initiation codes overlap on vertebrate core promoters. Nature\| PubMed ID: 24531765	2014
Computational characterization of modes of transcriptional regulation of nuclear receptor genes. PloS one\| PubMed ID: 24551185	2014
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. The Journal of clinical investigation\| PubMed ID: 24614105	2014
Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest. Molecular biology and evolution\| PubMed ID: 25525214	2015
CAGEr: precise TSS data retrieval and high-resolution promoterome mining for integrative analyses. Nucleic acids research\| PubMed ID: 25653163	2015
Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin. Genome research\| PubMed ID: 25677180	2015
Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome. Nature communications\| PubMed ID: 25908307	2015
Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene. Human genetics\| PubMed ID: 26337422	2015
JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles. Nucleic acids research\| PubMed ID: 26531826	2016
GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data. BMC genomics\| PubMed ID: 26576536	2015
Control of developmentally primed erythroid genes by combinatorial co-repressor actions. Nature communications\| PubMed ID: 26593974	2015
Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs. Nucleic acids research\| PubMed ID: 26673698	2016
Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia. Cancer cell\| PubMed ID: 26766589	2016
Promoter architectures and developmental gene regulation. Seminars in cell & developmental biology\| PubMed ID: 26783721	2016
TFBSTools: an R/bioconductor package for transcription factor binding site analysis. Bioinformatics (Oxford, England)\| PubMed ID: 26794315	2016
Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA-dependent Pre-transfer Editing. The Journal of biological chemistry\| PubMed ID: 26921320	2016
Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation. Genome biology\| PubMed ID: 28118853	2017
Core promoters across the genome. Nature biotechnology\| PubMed ID: 28178253	2017
Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation. Nature communications\| PubMed ID: 28874668	2017
Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells. The EMBO journal\| PubMed ID: 28978671	2017
Conserved non-coding elements: developmental gene regulation meets genome organization. Nucleic acids research\| PubMed ID: 29121339	2017
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic acids research\| PubMed ID: 29140473	2018
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic acids research\| PubMed ID: 29161433	2018
Distinct core promoter codes drive transcription initiation at key developmental transitions in a marine chordate. BMC genomics\| PubMed ID: 29482522	2018
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte. Nature\| PubMed ID: 29513657	2018
Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome. Genome research\| PubMed ID: 29618487	2018
BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells. Brain : a journal of neurology\| PubMed ID: 29985992	2018
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation. Nature immunology\| PubMed ID: 30127433	2018
SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA. Genome research\| PubMed ID: 30404778	2018
Amphioxus functional genomics and the origins of vertebrate gene regulation. Nature\| PubMed ID: 30464347	2018
A Novel Measure of Non-coding Genome Conservation Identifies Genomic Regulatory Blocks Within Primates. Bioinformatics (Oxford, England)\| PubMed ID: 30535005	2018
Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions. FEMS yeast research\| PubMed ID: 30590648	2019
DNA stretching induces Cas9 off-target activity. Nature structural & molecular biology\| PubMed ID: 30804513	2019
Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation. PLoS biology\| PubMed ID: 30978178	2019
Computation Resources for Molecular Biology: Special Issue 2019. Journal of molecular biology\| PubMed ID: 31152744	2019