Institute of Clinical Sciences,
Faculty of Medicine,
Institute of Clinical Sciences, Faculty of Medicine
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Making enhancers from spare parts of the genome.
Genome biology Dec, 2011 | Pubmed ID: 22206586
Metazoan promoters: emerging characteristics and insights into transcriptional regulation.
Nature reviews. Genetics Mar, 2012 | Pubmed ID: 22392219
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2012 | Pubmed ID: 22451944
A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.
Molecular and cellular biology Oct, 2012 | Pubmed ID: 22801375
OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica.
Nucleic acids research Jan, 2013 | Pubmed ID: 23185044
Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions.
Genome research May, 2013 | Pubmed ID: 23482648
r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data.
Nucleic acids research Jul, 2013 | Pubmed ID: 23671339
Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments.
Genome research Dec, 2013 | Pubmed ID: 24002784
JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles.
Nucleic acids research Jan, 2014 | Pubmed ID: 24194598
The mystery of extreme non-coding conservation.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Dec, 2013 | Pubmed ID: 24218634
Two independent transcription initiation codes overlap on vertebrate core promoters.
Nature Mar, 2014 | Pubmed ID: 24531765
Computational characterization of modes of transcriptional regulation of nuclear receptor genes.
PloS one , 2014 | Pubmed ID: 24551185
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers.
The Journal of clinical investigation Apr, 2014 | Pubmed ID: 24614105
Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest.
Molecular biology and evolution Mar, 2015 | Pubmed ID: 25525214
CAGEr: precise TSS data retrieval and high-resolution promoterome mining for integrative analyses.
Nucleic acids research Apr, 2015 | Pubmed ID: 25653163
Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin.
Genome research Apr, 2015 | Pubmed ID: 25677180
Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome.
Nature communications Apr, 2015 | Pubmed ID: 25908307
Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene.
Human genetics Nov, 2015 | Pubmed ID: 26337422
JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles.
Nucleic acids research Jan, 2016 | Pubmed ID: 26531826
GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data.
BMC genomics Nov, 2015 | Pubmed ID: 26576536
Control of developmentally primed erythroid genes by combinatorial co-repressor actions.
Nature communications Nov, 2015 | Pubmed ID: 26593974
Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs.
Nucleic acids research Apr, 2016 | Pubmed ID: 26673698
Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.
Cancer cell Jan, 2016 | Pubmed ID: 26766589
Promoter architectures and developmental gene regulation.
Seminars in cell & developmental biology 09, 2016 | Pubmed ID: 26783721
TFBSTools: an R/bioconductor package for transcription factor binding site analysis.
Bioinformatics (Oxford, England) 05, 2016 | Pubmed ID: 26794315
Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA-dependent Pre-transfer Editing.
The Journal of biological chemistry Apr, 2016 | Pubmed ID: 26921320
Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation.
Genome biology 01, 2017 | Pubmed ID: 28118853
Core promoters across the genome.
Nature biotechnology 02, 2017 | Pubmed ID: 28178253
Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation.
Nature communications 09, 2017 | Pubmed ID: 28874668
Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells.
The EMBO journal 11, 2017 | Pubmed ID: 28978671
Conserved non-coding elements: developmental gene regulation meets genome organization.
Nucleic acids research Dec, 2017 | Pubmed ID: 29121339
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework.
Nucleic acids research Jan, 2018 | Pubmed ID: 29140473
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework.
Nucleic acids research 01, 2018 | Pubmed ID: 29161433
Distinct core promoter codes drive transcription initiation at key developmental transitions in a marine chordate.
BMC genomics 02, 2018 | Pubmed ID: 29482522
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte.
Nature 03, 2018 | Pubmed ID: 29513657
Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome.
Genome research 05, 2018 | Pubmed ID: 29618487
BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells.
Brain : a journal of neurology Aug, 2018 | Pubmed ID: 29985992
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.
Nature immunology 09, 2018 | Pubmed ID: 30127433
SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA.
Genome research 12, 2018 | Pubmed ID: 30404778
Amphioxus functional genomics and the origins of vertebrate gene regulation.
Nature 12, 2018 | Pubmed ID: 30464347
A Novel Measure of Non-coding Genome Conservation Identifies Genomic Regulatory Blocks Within Primates.
Bioinformatics (Oxford, England) Dec, 2018 | Pubmed ID: 30535005
Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions.
FEMS yeast research 03, 2019 | Pubmed ID: 30590648
DNA stretching induces Cas9 off-target activity.
Nature structural & molecular biology Mar, 2019 | Pubmed ID: 30804513
Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.
PLoS biology Apr, 2019 | Pubmed ID: 30978178
Computation Resources for Molecular Biology: Special Issue 2019.
Journal of molecular biology Jun, 2019 | Pubmed ID: 31152744
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