Matthew W. Frank

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.

A Pseudomonas aeruginosa transcription factor that senses fatty acid structure.

PqsD is responsible for the synthesis of 2,4-dihydroxyquinoline, an extracellular metabolite produced by Pseudomonas aeruginosa.

Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis.

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors.

Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus.

Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice.

Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus.

FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus.

A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae.

Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis.

Chlamydia trachomatis Scavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase.

Maternal bile acid transporter deficiency promotes neonatal demise.

Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria.

Enoyl-Acyl Carrier Protein Reductase I (FabI) Is Essential for the Intracellular Growth of Listeria monocytogenes.

Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae.

Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation.

Role of Fatty Acid Kinase in Cellular Lipid Homeostasis and SaeRS-Dependent Virulence Factor Expression in .

A therapeutic approach to pantothenate kinase associated neurodegeneration.

Acyl-chain selectivity and physiological roles of fatty acid-binding proteins.

Oleate hydratase from protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.

A fatty acid binding protein of facilitates the acquisition of host polyunsaturated fatty acids.