Department of Infectious Diseases
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Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.
The Journal of biological chemistry Dec, 2004 | Pubmed ID: 15459190
A Pseudomonas aeruginosa transcription factor that senses fatty acid structure.
Molecular microbiology Nov, 2007 | Pubmed ID: 17877713
PqsD is responsible for the synthesis of 2,4-dihydroxyquinoline, an extracellular metabolite produced by Pseudomonas aeruginosa.
The Journal of biological chemistry Oct, 2008 | Pubmed ID: 18728009
Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis.
The Journal of biological chemistry Oct, 2009 | Pubmed ID: 19666474
Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2011 | Pubmed ID: 21876172
Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus.
Journal of bacteriology Oct, 2012 | Pubmed ID: 22843840
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice.
Antimicrobial agents and chemotherapy Nov, 2013 | Pubmed ID: 23979734
Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus.
Molecular microbiology Apr, 2014 | Pubmed ID: 24673884
FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus.
Antimicrobial agents and chemotherapy Feb, 2015 | Pubmed ID: 25403676
A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae.
Molecular microbiology Apr, 2015 | Pubmed ID: 25534847
Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis.
The Journal of biological chemistry Jul, 2015 | Pubmed ID: 25995447
Chlamydia trachomatis Scavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase.
The Journal of biological chemistry Sep, 2015 | Pubmed ID: 26195634
Maternal bile acid transporter deficiency promotes neonatal demise.
Nature communications Sep, 2015 | Pubmed ID: 26416771
Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria.
The Journal of biological chemistry Jan, 2016 | Pubmed ID: 26567338
Enoyl-Acyl Carrier Protein Reductase I (FabI) Is Essential for the Intracellular Growth of Listeria monocytogenes.
Infection and immunity Dec, 2016 | Pubmed ID: 27736774
Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae.
PLoS pathogens Oct, 2016 | Pubmed ID: 27760231
Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation.
Cell reports 06, 2017 | Pubmed ID: 28591579
Role of Fatty Acid Kinase in Cellular Lipid Homeostasis and SaeRS-Dependent Virulence Factor Expression in .
mBio 08, 2017 | Pubmed ID: 28765222
A therapeutic approach to pantothenate kinase associated neurodegeneration.
Nature communications 10, 2018 | Pubmed ID: 30352999
Acyl-chain selectivity and physiological roles of fatty acid-binding proteins.
The Journal of biological chemistry 01, 2019 | Pubmed ID: 30429218
Oleate hydratase from protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.
The Journal of biological chemistry Jun, 2019 | Pubmed ID: 31018965
A fatty acid binding protein of facilitates the acquisition of host polyunsaturated fatty acids.
The Journal of biological chemistry Sep, 2019 | Pubmed ID: 31530637
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