A.L.T.O. Nascimento

Novel Leptospira interrogans protein Lsa32 is expressed during infection and binds laminin and plasminogen.

Leptospira interrogans reduces fibrin clot formation by modulating human thrombin activity via exosite I.

The recombinant LIC10508 is a plasma fibronectin, plasminogen, fibrinogen and C4BP-binding protein of Leptospira interrogans.

Leptospira spp.: Novel insights into host-pathogen interactions.

Evaluation of two novel leptospiral proteins for their interaction with human host components.

Mammalian cell entry (Mce) protein of Leptospira interrogans binds extracellular matrix components, plasminogen and β2 integrin.

Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans.

Multifunctional and Redundant Roles of Leptospira interrogans Proteins in Bacterial-Adhesion and fibrin clotting inhibition.

The role of Lsa23 to mediate the interaction of Leptospira interrogans with the terminal complement components pathway.

Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans.

Proteomics as a tool to understand Leptospira physiology and virulence: Recent advances, challenges and clinical implications.

Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties.

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components.

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira.

Analysis of Genetic VapC Profiles from the Toxin-Antitoxin Type II VapBC Modules among Pathogenic, Intermediate, and Non-Pathogenic .

Adjuvanted leptospiral vaccines: Challenges and future development of new leptospirosis vaccines.

The Leptospira interrogans LIC10774 is a multifunctional surface protein that binds calcium and interacts with host components.