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Laboratório de Desenvolvimento de Vacinas
A.L.T.O. Nascimento has not added Biography.
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Novel Leptospira interrogans protein Lsa32 is expressed during infection and binds laminin and plasminogen.
Microbiology (Reading, England) Apr, 2015 | Pubmed ID: 25627443
Leptospira interrogans reduces fibrin clot formation by modulating human thrombin activity via exosite I.
Pathogens and disease Jun, 2015 | Pubmed ID: 25834144
The recombinant LIC10508 is a plasma fibronectin, plasminogen, fibrinogen and C4BP-binding protein of Leptospira interrogans.
Pathogens and disease Mar, 2016 | Pubmed ID: 26657108
Leptospira spp.: Novel insights into host-pathogen interactions.
Veterinary immunology and immunopathology Aug, 2016 | Pubmed ID: 26727033
Evaluation of two novel leptospiral proteins for their interaction with human host components.
Pathogens and disease 07, 2016 | Pubmed ID: 27129366
Mammalian cell entry (Mce) protein of Leptospira interrogans binds extracellular matrix components, plasminogen and β2 integrin.
Microbiology and immunology Sep, 2016 | Pubmed ID: 27468683
Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Apr, 2017 | Pubmed ID: 28161462
Multifunctional and Redundant Roles of Leptospira interrogans Proteins in Bacterial-Adhesion and fibrin clotting inhibition.
International journal of medical microbiology : IJMM Sep, 2017 | Pubmed ID: 28600123
The role of Lsa23 to mediate the interaction of Leptospira interrogans with the terminal complement components pathway.
Microbial pathogenesis Nov, 2017 | Pubmed ID: 28963011
Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans.
Molecular and cellular probes 02, 2018 | Pubmed ID: 29108931
Proteomics as a tool to understand Leptospira physiology and virulence: Recent advances, challenges and clinical implications.
Journal of proteomics 05, 2018 | Pubmed ID: 29501847
Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties.
International journal of medical microbiology : IJMM Mar, 2019 | Pubmed ID: 30638770
Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi Feb, 2020 | Pubmed ID: 30713004
Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira.
Scientific reports 02, 2019 | Pubmed ID: 30755626
Analysis of Genetic VapC Profiles from the Toxin-Antitoxin Type II VapBC Modules among Pathogenic, Intermediate, and Non-Pathogenic .
Microorganisms Feb, 2019 | Pubmed ID: 30791633
Adjuvanted leptospiral vaccines: Challenges and future development of new leptospirosis vaccines.
Vaccine 07, 2019 | Pubmed ID: 31186193
The Leptospira interrogans LIC10774 is a multifunctional surface protein that binds calcium and interacts with host components.
Microbiological research May, 2020 | Pubmed ID: 32247916
Instituto Butantan
L. G. V. Fernandes1,2,
R. L. Hornsby1,
A.L.T.O. Nascimento*,2,
J. E. Nally*,1
1Infectious Bacterial Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture,
2Laboratório de Desenvolvimento de Vacinas, Instituto Butantan
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