Stuart G. Campbell

Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.

Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways.

Mathematical modeling of aortic valve dynamics during systole.

Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes.

Slowing of contractile kinetics by myosin-binding protein C can be explained by its cooperative binding to the thin filament.

Modeling predicts a connection between sinus vortex effects and aortic compliance.

Contributions of Ca2+-Independent Thin Filament Activation to Cardiac Muscle Function.

Structural determinants of muscle thin filament cooperativity.

Anisotropic engineered heart tissue made from laser-cut decellularized myocardium.

Acute Optogenetic Modulation of Cardiac Twitch Dynamics Explored Through Modeling.

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

A Protocol for Collecting Human Cardiac Tissue for Research.

Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca-dependent manner.

Force-Dependent Recruitment from the Myosin Off State Contributes to Length-Dependent Activation.

Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting.

Diverse relaxation rates exist among rat cardiomyocytes isolated from a single myocardial region.

A short history of the development of mathematical models of cardiac mechanics.

Modelling sarcomeric cardiomyopathies with human cardiomyocytes derived from induced pluripotent stem cells.

Sarcomere-Directed Calcium Reporters in Cardiomyocytes.

The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time.

Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation.

Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes.

Cardiomyocyte d-dopachrome tautomerase protects against heart failure.

A Microwell Cell Capture Device Reveals Variable Response to Dobutamine in Isolated Cardiomyocytes.

Modular design of a tissue engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes.

KBTBD13 and the ever-expanding sarcomeric universe.

Polycystin 2 is increased in disease to protect against stress-induced cell death.

Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues.

Multiscale Modeling of Cardiovascular Function Predicts That the End-Systolic Pressure Volume Relationship Can Be Targeted via Multiple Therapeutic Strategies.

Fast-relaxing cardiomyocytes exert a dominant role in the relaxation behavior of heterogeneous myocardium.

Mavacamten preserves length-dependent contractility and improves diastolic function in human engineered heart tissue.

Potential impacts of the cardiac troponin I mobile domain on myofilament activation and relaxation.

Evidence for synergy between sarcomeres and fibroblasts in an in vitro model of myocardial reverse remodeling.

Danicamtiv Enhances Systolic Function and Frank-Starling Behavior at Minimal Diastolic Cost in Engineered Human Myocardium.

Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation.

Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains.

MicroRNA function can be reversed by altering target gene expression levels.

Functional and structural differences between skinned and intact muscle preparations.