Program in Molecular Pathogenesis
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Costimulation and endogenous MHC ligands contribute to T cell recognition.
Nature immunology Jan, 2002 | Pubmed ID: 11731799
Membrane domains and the immunological synapse: keeping T cells resting and ready.
The Journal of clinical investigation Jan, 2002 | Pubmed ID: 11805125
T cell receptor signaling precedes immunological synapse formation.
Science (New York, N.Y.) Feb, 2002 | Pubmed ID: 11859198
WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation.
Immunity Feb, 2002 | Pubmed ID: 11869681
Polar redistribution of the sialoglycoprotein CD43: implications for T cell function.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2002 | Pubmed ID: 11937524
Stimulation of naïve T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms.
Immunology Jul, 2002 | Pubmed ID: 12100716
The immunological synapse.
Arthritis research , 2002 | Pubmed ID: 12110130
Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation.
Immunity Jun, 2002 | Pubmed ID: 12121665
Shmoos, rafts, and uropods- the many facets of cell polarity.
Cell Jul, 2002 | Pubmed ID: 12150993
Cutting edge: quantitative imaging of raft accumulation in the immunological synapse.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2002 | Pubmed ID: 12218094
T-cell activation: a multidimensional signaling network.
Current opinion in cell biology Oct, 2002 | Pubmed ID: 12231352
The immunological synapse: integrins take the stage.
Immunological reviews Aug, 2002 | Pubmed ID: 12234366
Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation.
Trends in immunology Oct, 2002 | Pubmed ID: 12297421
The synapse assembly model.
Trends in immunology Oct, 2002 | Pubmed ID: 12297422
Neural and immunological synaptic relations.
Science (New York, N.Y.) Oct, 2002 | Pubmed ID: 12399580
Regulation of T cell migration through formation of immunological synapses: the stop signal hypothesis.
Advances in experimental medicine and biology , 2002 | Pubmed ID: 12405204
Coordination of T cell activation and migration through formation of the immunological synapse.
Annals of the New York Academy of Sciences Apr, 2003 | Pubmed ID: 12727623
In vivo imaging approaches in animal models of rheumatoid arthritis.
Arthritis research & therapy , 2003 | Pubmed ID: 12823846
Supported planar bilayers in studies on immune cell adhesion and communication.
Journal of immunological methods Jul, 2003 | Pubmed ID: 12957393
The immunological synapse balances T cell receptor signaling and degradation.
Science (New York, N.Y.) Nov, 2003 | Pubmed ID: 14512504
In silico models for cellular and molecular immunology: successes, promises and challenges.
Nature immunology Oct, 2003 | Pubmed ID: 14515121
Cytotoxic T lymphocytes form an antigen-independent ring junction.
The Journal of clinical investigation Jan, 2004 | Pubmed ID: 14702108
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.
Nature immunology Mar, 2004 | Pubmed ID: 14973438
Membranes as messengers in T cell adhesion signaling.
Nature immunology Apr, 2004 | Pubmed ID: 15052266
LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation.
Immunity May, 2004 | Pubmed ID: 15142527
What is the importance of the immunological synapse?
Trends in immunology Jun, 2004 | Pubmed ID: 15145322
T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation.
The Journal of cell biology Aug, 2004 | Pubmed ID: 15314068
Stop and go traffic to tune T cell responses.
Immunity Sep, 2004 | Pubmed ID: 15357942
A polarizing situation.
Nature immunology Oct, 2004 | Pubmed ID: 15454929
Visualizing dendritic cell networks in vivo.
Nature immunology Dec, 2004 | Pubmed ID: 15543150
Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids.
PLoS biology Apr, 2005 | Pubmed ID: 15799695
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America May, 2005 | Pubmed ID: 15851656
ICAM-1 co-stimulates target cells to facilitate antigen presentation.
Current opinion in immunology Jun, 2005 | Pubmed ID: 15886114
ATP mediates rapid microglial response to local brain injury in vivo.
Nature neuroscience Jun, 2005 | Pubmed ID: 15895084
A model for CD2/CD58-mediated adhesion strengthening.
Annals of biomedical engineering Apr, 2005 | Pubmed ID: 15909654
Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo.
Nature immunology Jul, 2005 | Pubmed ID: 15924144
A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.
Novartis Foundation symposium , 2005 | Pubmed ID: 15999806
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.
The Journal of experimental medicine Oct, 2005 | Pubmed ID: 16216891
A dynamic view of the immunological synapse.
Seminars in immunology Dec, 2005 | Pubmed ID: 16266811
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.
Nature immunology Dec, 2005 | Pubmed ID: 16273097
Altered TCR signaling from geometrically repatterned immunological synapses.
Science (New York, N.Y.) Nov, 2005 | Pubmed ID: 16293763
CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2005 | Pubmed ID: 16339518
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo.
The Journal of experimental medicine Mar, 2006 | Pubmed ID: 16533880
T cells like a firm molecular handshake.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2006 | Pubmed ID: 16537367
T cell-dendritic cell immunological synapses.
Current opinion in immunology Aug, 2006 | Pubmed ID: 16777399
Dynamic imaging of the immune system: progress, pitfalls and promise.
Nature reviews. Immunology Jul, 2006 | Pubmed ID: 16799470
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.
Immunity Jul, 2006 | Pubmed ID: 16860761
Immunology. When F-actin becomes too much of a good thing.
Science (New York, N.Y.) Aug, 2006 | Pubmed ID: 16902113
Lateral membrane waves constitute a universal dynamic pattern of motile cells.
Physical review letters Jul, 2006 | Pubmed ID: 16907546
Innate response to focal necrotic injury inside the blood-brain barrier.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2006 | Pubmed ID: 17015712
Impact of the immunological synapse on T cell signaling.
Results and problems in cell differentiation , 2006 | Pubmed ID: 17068972
Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2006 | Pubmed ID: 17077145
Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules.
Biophysical journal Feb, 2007 | Pubmed ID: 17085486
Control of antigen presentation with a photoreleasable agonist peptide.
Journal of the American Chemical Society Dec, 2006 | Pubmed ID: 17131984
Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion.
ACS chemical biology Nov, 2006 | Pubmed ID: 17168569
Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells.
Immunity Jan, 2007 | Pubmed ID: 17241958
In vivo imaging of germinal centres reveals a dynamic open structure.
Nature Mar, 2007 | Pubmed ID: 17268470
The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.
Nature cell biology Jun, 2007 | Pubmed ID: 17486117
Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse.
Cell May, 2007 | Pubmed ID: 17512410
Requirements for T lymphocyte migration in explanted lymph nodes.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2007 | Pubmed ID: 17548612
Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.
Immunological reviews Aug, 2007 | Pubmed ID: 17624948
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes.
Nature immunology Aug, 2007 | Pubmed ID: 17632517
Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion.
The Journal of biological chemistry Nov, 2007 | Pubmed ID: 17911103
Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses.
Current opinion in cell biology Oct, 2007 | Pubmed ID: 17923403
Dynamics of host defense: the view at the front lines.
Nature immunology Nov, 2007 | Pubmed ID: 17952039
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18077330
Tug of war at the exit door.
Immunity Jan, 2008 | Pubmed ID: 18199414
T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation.
Biophysical journal Apr, 2008 | Pubmed ID: 18199675
Cutting edge: activation by innate cytokines or microbial antigens can cause arrest of natural killer T cell patrolling of liver sinusoids.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2008 | Pubmed ID: 18250405
T-cell activation through immunological synapses and kinapses.
Immunological reviews Feb, 2008 | Pubmed ID: 18275476
Synaptic asymmetry to go.
Cell Mar, 2008 | Pubmed ID: 18329360
Measuring diffusion and binding kinetics by contact area FRAP.
Biophysical journal Jul, 2008 | Pubmed ID: 18390627
A coupled diffusion-kinetics model for analysis of contact-area FRAP experiment.
Biophysical journal Jul, 2008 | Pubmed ID: 18390628
Supported planar bilayers for study of the immunological synapse.
Current protocols in immunology / edited by John E. Coligan ... [et al.] Feb, 2007 | Pubmed ID: 18432988
Micropatterning of costimulatory ligands enhances CD4+ T cell function.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2008 | Pubmed ID: 18505845
Th1 and Th2 cells form morphologically distinct immunological synapses.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2008 | Pubmed ID: 18566405
Hunter to gatherer and back: immunological synapses and kinapses as variations on the theme of amoeboid locomotion.
Annual review of cell and developmental biology , 2008 | Pubmed ID: 18598213
Human immunodeficiency virus type 1 envelope gp120 induces a stop signal and virological synapse formation in noninfected CD4+ T cells.
Journal of virology Oct, 2008 | Pubmed ID: 18632854
Modulation of T cell activation by stomatin-like protein 2.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2008 | Pubmed ID: 18641330
Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2008 | Pubmed ID: 18713980
Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802085
T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802089
Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse.
The Journal of biological chemistry Dec, 2008 | Pubmed ID: 18826951
Lrp4 is a receptor for Agrin and forms a complex with MuSK.
Cell Oct, 2008 | Pubmed ID: 18848351
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.
Immunity Oct, 2008 | Pubmed ID: 18848472
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis.
Nature Jan, 2009 | Pubmed ID: 19011611
Visualization of cell-cell interaction contacts-synapses and kinapses.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 19065791
Renal dendritic cells: an update.
Nephron. Experimental nephrology , 2009 | Pubmed ID: 19276627
Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane.
Molecular and cellular biology Jun, 2009 | Pubmed ID: 19332557
T cell antigen receptor signaling and immunological synapse stability require myosin IIA.
Nature immunology May, 2009 | Pubmed ID: 19349987
Visualizing immune system complexity.
Science signaling , 2009 | Pubmed ID: 19366990
The cellular context of T cell signaling.
Immunity Apr, 2009 | Pubmed ID: 19371714
The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells.
The Journal of cell biology May, 2009 | Pubmed ID: 19398758
Supported bilayers at the vanguard of immune cell activation studies.
Journal of structural biology Oct, 2009 | Pubmed ID: 19500675
Multiscale analysis of T cell activation: correlating in vitro and in vivo analysis of the immunological synapse.
Current topics in microbiology and immunology , 2009 | Pubmed ID: 19521681
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Nature Jun, 2009 | Pubmed ID: 19536265
The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.
Molecular biology of the cell Sep, 2009 | Pubmed ID: 19587117
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.
Immunity Jul, 2009 | Pubmed ID: 19592272
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo.
The Journal of experimental medicine Aug, 2009 | Pubmed ID: 19667061
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19706535
Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.
Journal of virology Nov, 2009 | Pubmed ID: 19710135
Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites.
Journal of immunological methods Jan, 2010 | Pubmed ID: 19800886
Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain.
Immunity Oct, 2009 | Pubmed ID: 19833088
Insights into function of the immunological synapse from studies with supported planar bilayers.
Current topics in microbiology and immunology , 2010 | Pubmed ID: 19960306
Functional anatomy of T cell activation and synapse formation.
Annual review of immunology Mar, 2010 | Pubmed ID: 19968559
Modular design of immunological synapses and kinapses.
Cold Spring Harbor perspectives in biology Jul, 2009 | Pubmed ID: 20066081
Protein kinase C-theta mediates negative feedback on regulatory T cell function.
Science (New York, N.Y.) Apr, 2010 | Pubmed ID: 20339032
Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster.
Immunity Apr, 2010 | Pubmed ID: 20399684
Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2010 | Pubmed ID: 20435926
Affinity measured by microcluster.
The Journal of experimental medicine May, 2010 | Pubmed ID: 20439542
Cytotoxic immunological synapses.
Immunological reviews May, 2010 | Pubmed ID: 20536553
High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells.
Molecular membrane biology Aug, 2010 | Pubmed ID: 20540668
Development and migration of plasma cells in the mouse lymph node.
Immunity Jul, 2010 | Pubmed ID: 20619695
Understanding the structure and function of the immunological synapse.
Cold Spring Harbor perspectives in biology Oct, 2010 | Pubmed ID: 20843980
HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse.
Viruses May, 2010 | Pubmed ID: 20890395
Signaling microdomains in T cells.
FEBS letters Dec, 2010 | Pubmed ID: 20965175
CTLs respond with activation and granule secretion when serving as targets for T-cell recognition.
Blood Jan, 2011 | Pubmed ID: 21045195
Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter.
Cell Nov, 2010 | Pubmed ID: 21074050
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.
Science (New York, N.Y.) Apr, 2011 | Pubmed ID: 21393509
Dynamic imaging of the effector immune response to listeria infection in vivo.
PLoS pathogens Mar, 2011 | Pubmed ID: 21455492
Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection.
The Journal of experimental medicine Apr, 2011 | Pubmed ID: 21464219
Induction by IL 1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254.
Journal of immunology (Baltimore, Md. : 1950) May, 2011 | Pubmed ID: 21505214
A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 1986. 137: 1270-1274.
Journal of immunology (Baltimore, Md. : 1950) May, 2011 | Pubmed ID: 21505215
Nanoengineering of Immune Cell Function.
Materials Research Society symposia proceedings. Materials Research Society Jan, 2009 | Pubmed ID: 21562611
A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center.
The Journal of experimental medicine Jun, 2011 | Pubmed ID: 21576382
T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.
Proceedings of the National Academy of Sciences of the United States of America May, 2011 | Pubmed ID: 21576490
A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies.
PloS one , 2011 | Pubmed ID: 21629715
The critical role of agrin in the hematopoietic stem cell niche.
Blood Sep, 2011 | Pubmed ID: 21653324
PKC-θ function at the immunological synapse: prospects for therapeutic targeting.
Trends in immunology Aug, 2011 | Pubmed ID: 21733754
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain.
The Journal of experimental medicine Aug, 2011 | Pubmed ID: 21788405
Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses.
PLoS computational biology Aug, 2011 | Pubmed ID: 21829338
HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA).
PloS one , 2011 | Pubmed ID: 21850260
New insights into the T cell synapse from single molecule techniques.
Nature reviews. Immunology Oct, 2011 | Pubmed ID: 21904389
PKC-θ: hitting the bull's eye.
Nature immunology Nov, 2011 | Pubmed ID: 22012436
Integrin inside-out signaling and the immunological synapse.
Current opinion in cell biology Nov, 2011 | Pubmed ID: 22129583
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2012 | Pubmed ID: 22223661
Immunology. Antigen feast or famine.
Science (New York, N.Y.) Jan, 2012 | Pubmed ID: 22282794
Visualization of Cell-Cell Interaction Contacts: Synapses and Kinapses.
Self/nonself 4, 2011 | Pubmed ID: 22299060
Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2012 | Pubmed ID: 22307621
Self-reactive human CD4 T cell clones form unusual immunological synapses.
The Journal of experimental medicine Feb, 2012 | Pubmed ID: 22312112
Mechanosensing in T lymphocyte activation.
Biophysical journal Jan, 2012 | Pubmed ID: 22339876
PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis.
The Journal of experimental medicine Apr, 2013 | Pubmed ID: 23530125
Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility.
Molecular and cellular biology Mar, 2014 | Pubmed ID: 24379441
TCR signaling: the barrier within.
Nature immunology Feb, 2014 | Pubmed ID: 24448571
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse.
Nature Mar, 2014 | Pubmed ID: 24487619
How T cells lose their touch.
Immunity Feb, 2014 | Pubmed ID: 24560192
What counts in the immunological synapse?
Molecular cell Apr, 2014 | Pubmed ID: 24766889
CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2014 | Pubmed ID: 25355918
The immunological synapse.
Cancer immunology research Nov, 2014 | Pubmed ID: 25367977
Force and affinity in ligand discrimination by the TCR.
Trends in immunology 12, 2014 | Pubmed ID: 25466309
T cells have a light touch.
Biophysical journal May, 2015 | Pubmed ID: 25954864
Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.
PLoS pathogens , 2015 | Pubmed ID: 26562533
Agile CD22 nanoclusters run rings around fenced BCR.
The EMBO journal Feb, 2016 | Pubmed ID: 26746852
Phagocytes Get Close to Their Enemies.
Developmental cell Jan, 2016 | Pubmed ID: 26812012
High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography.
Nano letters Apr, 2016 | Pubmed ID: 26990380
CELL SIGNALING. Liquidity in immune cell signaling.
Science (New York, N.Y.) Apr, 2016 | Pubmed ID: 27126023
Tapping out a mechanical code for T cell triggering.
The Journal of cell biology 06, 2016 | Pubmed ID: 27269063
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
The Journal of clinical investigation Jul, 2016 | Pubmed ID: 27294527
Force Bistability in Adhesion Switch.
Biophysical journal 09, 2016 | Pubmed ID: 27602717
HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation.
Journal of virology Dec, 2016 | Pubmed ID: 27630246
Complement Receptors in Myeloid Cell Adhesion and Phagocytosis.
Microbiology spectrum 11, 2016 | Pubmed ID: 27809953
Help to go: T cells transfer CD40L to antigen-presenting B cells.
European journal of immunology 01, 2017 | Pubmed ID: 28004382
The Immune Synapse: Past, Present, and Future.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28255692
Spatial Control of Biological Ligands on Surfaces Applied to T Cell Activation.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28255709
Comprehensive Analysis of Immunological Synapse Phenotypes Using Supported Lipid Bilayers.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28255717
Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity.
Scientific reports 06, 2017 | Pubmed ID: 28652577
Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer.
Cell reports 07, 2017 | Pubmed ID: 28723561
Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse.
Cell reports 01, 2018 | Pubmed ID: 29320731
A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling.
Frontiers in immunology , 2018 | Pubmed ID: 29456532
Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering.
Nature nanotechnology 07, 2018 | Pubmed ID: 29713075
Distinct behavior of myelomonocytic cells and CD8 T cells underlies the hepatic response to .
Wellcome open research , 2018 | Pubmed ID: 29862325
Natural killers shed attachments to kill again.
The Journal of cell biology 09, 2018 | Pubmed ID: 30108125
Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function.
Advances in immunology , 2018 | Pubmed ID: 30366518
CD8 helps TCR catch slippery self pMHC.
Nature immunology 12, 2018 | Pubmed ID: 30420625
CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.
Science signaling 12, 2018 | Pubmed ID: 30563863
Integrins and Their Role in Immune Cell Adhesion.
Cell 04, 2019 | Pubmed ID: 30952447
An X-ray Vision for Phosphoantigen Recognition.
Immunity 04, 2019 | Pubmed ID: 30995494
Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts.
Journal of immunology (Baltimore, Md. : 1950) 08, 2019 | Pubmed ID: 31201237
Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity.
Scientific reports Feb, 2020 | Pubmed ID: 32076101
A checkpoint cliffhanger at the dawn of placental mammals.
The Journal of biological chemistry 04, 2020 | Pubmed ID: 32245902
Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells.
Science (New York, N.Y.) 05, 2020 | Pubmed ID: 32381591
A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals.
Nature immunology 10, 2020 | Pubmed ID: 32929275
Author Correction: A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals.
Nature immunology Jan, 2021 | Pubmed ID: 33122852
Locked and loaded: strong TCR signaling primes anti-PD-1 therapy.
Trends in immunology Dec, 2021 | Pubmed ID: 34772621
The interplay between membrane topology and mechanical forces in regulating T cell receptor activity.
Communications biology 01, 2022 | Pubmed ID: 35017678
Dephosphorylation accelerates the dissociation of ZAP70 from the T cell receptor.
Proceedings of the National Academy of Sciences of the United States of America 03, 2022 | Pubmed ID: 35197288
Magnesium for T cells: strong to the finish!
Trends in immunology Apr, 2022 | Pubmed ID: 35260350
Kathleen C. Prins*,1,2,
Gaia Vasiliver-Shamis*,2,3,
Michael Cammer1,2,
David Depoil1,2,
Michael L. Dustin2,
Catarina E. Hioe1,4
1Department of Pathology, New York University Langone School of Medicine,
2Program in Molecular Pathogenesis, Marty and Helen Kimmel Center for Biology and Medicine and Skirball Institute for Biomolecular Medicine,
3Laboratory of Molecular Immunogenetics, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health,
4, Veteran Affairs New York Harbor Healthcare System
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