Department of Pathology
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High levels of antibodies to the CD4 binding domain of human immunodeficiency virus type 1 glycoprotein 120 are associated with faster disease progression.
The Journal of infectious diseases Jul, 2002 | Pubmed ID: 12134256
Propagation of CD4+ T cells specific for HIV type 1 envelope gp120 from chronically HIV type 1-infected subjects.
AIDS research and human retroviruses Sep, 2003 | Pubmed ID: 14585210
HIV-1-infected patients with envelope-specific lymphoproliferation or long-term nonprogression lack antibodies suppressing glycoprotein 120 antigen presentation.
The Journal of infectious diseases Mar, 2004 | Pubmed ID: 14976603
Human immunodeficiency virus type 1 evades T-helper responses by exploiting antibodies that suppress antigen processing.
Journal of virology Jul, 2004 | Pubmed ID: 15220439
Characterization of antibodies that inhibit HIV gp120 antigen processing and presentation.
European journal of immunology Sep, 2005 | Pubmed ID: 16106369
The antigenic determinants on HIV p24 for CD4+ T cell inhibiting antibodies as determined by limited proteolysis, chemical modification, and mass spectrometry.
Journal of the American Society for Mass Spectrometry Nov, 2006 | Pubmed ID: 16875837
Antigen stimulation induces HIV envelope gp120-specific CD4(+) T cells to secrete CCR5 ligands and suppress HIV infection.
Virology Dec, 2007 | Pubmed ID: 17765942
In vivo alteration of humoral responses to HIV-1 envelope glycoprotein gp120 by antibodies to the CD4-binding site of gp120.
Virology Mar, 2008 | Pubmed ID: 18054978
Identification of an N-linked glycosylation in the C4 region of HIV-1 envelope gp120 that is critical for recognition of neighboring CD4 T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2008 | Pubmed ID: 18322210
Human immunodeficiency virus type 1 envelope gp120 induces a stop signal and virological synapse formation in noninfected CD4+ T cells.
Journal of virology Oct, 2008 | Pubmed ID: 18632854
Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response.
Infectious agents and cancer , 2008 | Pubmed ID: 18638381
The differential binding and activity of PRO 2000 against diverse HIV-1 envelopes.
Journal of acquired immune deficiency syndromes (1999) Jun, 2009 | Pubmed ID: 19349871
Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes.
Journal of immunology (Baltimore, Md. : 1950) May, 2009 | Pubmed ID: 19414790
Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.
Journal of virology Nov, 2009 | Pubmed ID: 19710135
Anti-leukemia activity of a bacterial toxin with natural specificity for LFA-1 on white blood cells.
Leukemia research Jun, 2010 | Pubmed ID: 19747730
The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120.
Vaccine Dec, 2009 | Pubmed ID: 19879224
Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes.
PloS one , 2010 | Pubmed ID: 20421997
HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse.
Viruses May, 2010 | Pubmed ID: 20890395
Quantitative assessment of masking of neutralization epitopes in HIV-1.
Vaccine Sep, 2011 | Pubmed ID: 21216319
HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA).
PloS one , 2011 | Pubmed ID: 21850260
Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation.
Vaccine Nov, 2011 | Pubmed ID: 21945958
HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2011 | Pubmed ID: 21957147
In Vitro Restoration of Th17 Response During HIV Infection with an Antiretroviral Drug and Th17 Differentiation Cytokines.
AIDS research and human retroviruses Dec, 2011 | Pubmed ID: 22011036
Kathleen C. Prins*,1,2,
Gaia Vasiliver-Shamis*,2,3,
Michael Cammer1,2,
David Depoil1,2,
Michael L. Dustin2,
Catarina E. Hioe1,4
1Department of Pathology, New York University Langone School of Medicine,
2Program in Molecular Pathogenesis, Marty and Helen Kimmel Center for Biology and Medicine and Skirball Institute for Biomolecular Medicine,
3Laboratory of Molecular Immunogenetics, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health,
4, Veteran Affairs New York Harbor Healthcare System
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