Alvin C. Powers

Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line.

Ascorbic acid recycling by cultured beta cells: effects of increased glucose metabolism.

Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging.

Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice.

Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.

Glucose metabolism in vivo in four commonly used inbred mouse strains.

Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo.

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.

Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice.

Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation.

VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue.

The MafA transcription factor becomes essential to islet β-cells soon after birth.

Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding.

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

Suppression of insulin production and secretion by a decretin hormone.

Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish.

The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.

p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.

Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.

Replicative capacity of β-cells and type 1 diabetes.

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas.

Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity.

Signals in the pancreatic islet microenvironment influence β-cell proliferation.

Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.

Structural abnormalities in islets from very young children with cystic fibrosis may contribute to cystic fibrosis-related diabetes.

The obesity epidemic and rising diabetes incidence in a low-income racially diverse southern US cohort.

β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes.

Use of human islets to understand islet biology and diabetes: progress, challenges and suggestions.

Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice.

Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.

Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose.

Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells.

Decreased pancreatic acinar cell number in type 1 diabetes.

Dapagliflozin Does Not Directly Affect Human α or β Cells.

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells.

RIPK3-mediated inflammation is a conserved β cell response to ER stress.

COVID-19 vaccine prioritisation for type 1 and type 2 diabetes.

Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.

Type 1 diabetes mellitus: much progress, many opportunities.

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration.

Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes?

The Human Islet: Mini-Organ With Mega-Impact.

Endocrine toxicities of immune checkpoint inhibitors.

What is a β cell? - Chapter I in the Human Islet Research Network (HIRN) review series.

Debates in Pancreatic Beta Cell Biology: Proliferation Versus Progenitor Differentiation and Transdifferentiation in Restoring β Cell Mass.

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells.

Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.

Microvessels enhance vascularization and function of transplanted insulin-producing cells.

Understanding islet dysfunction in type 2 diabetes through multidimensional pancreatic phenotyping: The Human Pancreas Analysis Program.

Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas.

AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.

Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.

Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.

Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.