Julie A. Moreno

Intranasally delivered mesenchymal stromal cells decrease glial inflammation early in prion disease.

Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signaling pathways.

Nuclear factor kappa-B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low-level inflammatory stimulation with MPTP.

Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apoptosis.

Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes.

Age-dependent susceptibility to manganese-induced neurological dysfunction.

Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration.

Manganese-induced NF-kappaB activation and nitrosative stress is decreased by estrogen in juvenile mice.

Gene deletion of nos2 protects against manganese-induced neurological dysfunction in juvenile mice.

The chaperone Grp78 in protein folding disorders of the nervous system.

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.

Molecular Mechanisms of Chronic Wasting Disease Prion Propagation.

Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases.

Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis.

Compensatory Expression of Nur77 and Nurr1 Regulates NF-B-Dependent Inflammatory Signaling in Astrocytes.

Primary structural differences at residue 226 of deer and elk PrP dictate selection of distinct CWD prion strains in gene-targeted mice.

The cellular prion protein promotes neuronal regeneration after acute nasotoxic injury.

Network Simulations Reveal Molecular Signatures of Vulnerability to Age-Dependent Stress and Tau Accumulation.

Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein.

Tissue-specific biochemical differences between chronic wasting disease prions isolated from free-ranging white-tailed deer (Odocoileus virginianus).

Nontransgenic Guinea Pig Strains Exhibit Hallmarks of Human Brain Aging and Alzheimer's Disease.

Assessment of risk factors in dogs with presumptive advanced canine cognitive dysfunction.

Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro.

Gliosis, misfolded protein aggregation, and neuronal loss in a guinea pig model of pulmonary tuberculosis.

Activated gliosis, accumulation of amyloid β, and hyperphosphorylation of tau in aging canines with and without cognitive decline.