Paul R. Race

Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954.

Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy.

Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.

Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.

Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria.

Insertion of the enteropathogenic Escherichia coli Tir virulence protein into membranes in vitro.

Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954.

Conformation of the EPEC Tir protein in solution: investigating the impact of serine phosphorylation at positions 434/463.

Molecular architecture of the "stressosome," a signal integration and transduction hub.

Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism.

Solution structure of the major (Spy0128) and minor (Spy0125 and Spy0130) pili subunits from Streptococcus pyogenes.

Crystal structures of Cif from bacterial pathogens Photorhabdus luminescens and Burkholderia pseudomallei.