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School of Biochemistry
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Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954.
Cancer research Sep, 2003 | Pubmed ID: 14500391
Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy.
Journal of medicinal chemistry Nov, 2003 | Pubmed ID: 14584930
Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.
Clinical and experimental pharmacology & physiology Nov, 2004 | Pubmed ID: 15566399
Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15684426
Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria.
The Journal of biological chemistry Oct, 2005 | Pubmed ID: 16093240
Insertion of the enteropathogenic Escherichia coli Tir virulence protein into membranes in vitro.
The Journal of biological chemistry Mar, 2006 | Pubmed ID: 16436373
Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954.
Journal of molecular biology Apr, 2007 | Pubmed ID: 17350040
Conformation of the EPEC Tir protein in solution: investigating the impact of serine phosphorylation at positions 434/463.
Biophysical journal Jul, 2007 | Pubmed ID: 17449672
Molecular architecture of the "stressosome," a signal integration and transduction hub.
Science (New York, N.Y.) Oct, 2008 | Pubmed ID: 18832644
Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism.
The Journal of biological chemistry Mar, 2009 | Pubmed ID: 19129180
Solution structure of the major (Spy0128) and minor (Spy0125 and Spy0130) pili subunits from Streptococcus pyogenes.
European biophysics journal : EBJ Feb, 2010 | Pubmed ID: 19290517
Crystal structures of Cif from bacterial pathogens Photorhabdus luminescens and Burkholderia pseudomallei.
PloS one , 2009 | Pubmed ID: 19440549
University of Bristol
Marisa Till1,
Alice Robson1,
Matthew J. Byrne1,
Asha V. Nair1,
Stefan A. Kolek2,
Patrick D. Shaw Stewart2,
Paul R. Race1
1School of Biochemistry, University of Bristol,
2, Douglas Instruments
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