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Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis.
Development (Cambridge, England) Jan, 2002 | Pubmed ID: 11782411
Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.
Genes & development Feb, 2002 | Pubmed ID: 11825878
Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling.
Development (Cambridge, England) Feb, 2002 | Pubmed ID: 11861468
CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.
Molecular and cellular biology Mar, 2002 | Pubmed ID: 11865058
Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein.
Current biology : CB Apr, 2002 | Pubmed ID: 11937021
The promise and perils of Wnt signaling through beta-catenin.
Science (New York, N.Y.) May, 2002 | Pubmed ID: 12040179
Cellular processes associated with germ band retraction in Drosophila.
Developmental biology Aug, 2002 | Pubmed ID: 12142018
Molecular mechanisms of epithelial morphogenesis.
Annual review of cell and developmental biology , 2002 | Pubmed ID: 12142280
Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila.
Development (Cambridge, England) Sep, 2002 | Pubmed ID: 12183376
Hedgehog signal transduction: recent findings.
Current opinion in genetics & development Oct, 2002 | Pubmed ID: 12200154
Unconventional ways to travel.
Nature cell biology Sep, 2002 | Pubmed ID: 12205482
Analysis of twenty-four Gal4 lines in Drosophila melanogaster.
Genesis (New York, N.Y. : 2000) Sep-Oct, 2002 | Pubmed ID: 12324947
Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila.
Biochimica et biophysica acta Dec, 2002 | Pubmed ID: 12417410
Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2003 | Pubmed ID: 12424225
Sequential activation of signaling pathways during innate immune responses in Drosophila.
Developmental cell Nov, 2002 | Pubmed ID: 12431377
A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding.
Neuron Nov, 2002 | Pubmed ID: 12441051
The Jak/STAT pathway in model organisms: emerging roles in cell movement.
Developmental cell Dec, 2002 | Pubmed ID: 12479803
Roles of myosin phosphatase during Drosophila development.
Development (Cambridge, England) Feb, 2003 | Pubmed ID: 12505998
Integrated activity of PDZ protein complexes regulates epithelial polarity.
Nature cell biology Jan, 2003 | Pubmed ID: 12510194
The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila.
Genetics Dec, 2002 | Pubmed ID: 12524343
Tailoring the genome: the power of genetic approaches.
Nature genetics Mar, 2003 | Pubmed ID: 12610537
Retraction of the Drosophila germ band requires cell-matrix interaction.
Genes & development Mar, 2003 | Pubmed ID: 12629042
The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila.
Development (Cambridge, England) Jun, 2003 | Pubmed ID: 12702654
Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis.
Developmental biology Jul, 2003 | Pubmed ID: 12812783
Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.
The EMBO journal Jul, 2003 | Pubmed ID: 12853478
Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.
Development (Cambridge, England) Sep, 2003 | Pubmed ID: 12900463
neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions.
Development (Cambridge, England) Oct, 2003 | Pubmed ID: 12917292
Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.
Developmental cell Sep, 2003 | Pubmed ID: 12967563
Developmental roles of heparan sulfate proteoglycans in Drosophila.
Glycoconjugate journal May-Jun, 2002 | Pubmed ID: 12975617
Apicobasal polarization: epithelial form and function.
Current opinion in cell biology Dec, 2003 | Pubmed ID: 14644201
A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway.
Genetics Nov, 2003 | Pubmed ID: 14668372
Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis.
Nature immunology Jan, 2004 | Pubmed ID: 14691479
Genome-wide RNAi analysis of growth and viability in Drosophila cells.
Science (New York, N.Y.) Feb, 2004 | Pubmed ID: 14764878
Wingless, hedgehog and heparan sulfate proteoglycans.
Development (Cambridge, England) Jun, 2004 | Pubmed ID: 15148297
Temperature-sensitive control of protein activity by conditionally splicing inteins.
Nature biotechnology Jul, 2004 | Pubmed ID: 15184905
The roles of JAK/STAT signaling in Drosophila immune responses.
Immunological reviews Apr, 2004 | Pubmed ID: 15199955
The PDGF/VEGF receptor controls blood cell survival in Drosophila.
Developmental cell Jul, 2004 | Pubmed ID: 15239955
Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development.
Developmental biology Sep, 2004 | Pubmed ID: 15302597
Genome-wide high-throughput screens in functional genomics.
Current opinion in genetics & development Oct, 2004 | Pubmed ID: 15380236
Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila.
Developmental cell Oct, 2004 | Pubmed ID: 15469842
Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research.
Oncogene Nov, 2004 | Pubmed ID: 15517017
The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.
Developmental biology Dec, 2004 | Pubmed ID: 15531366
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets.
PLoS biology Dec, 2004 | Pubmed ID: 15547975
High-throughput RNA interference screens in Drosophila tissue culture cells.
Methods in enzymology , 2005 | Pubmed ID: 15644175
Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition.
Genes & development Feb, 2005 | Pubmed ID: 15713840
Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.
Development (Cambridge, England) Apr, 2005 | Pubmed ID: 15772135
Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing.
Science (New York, N.Y.) Mar, 2005 | Pubmed ID: 15774762
Functional genomic analysis of the Wnt-wingless signaling pathway.
Science (New York, N.Y.) May, 2005 | Pubmed ID: 15817814
Drosophila Wnt/Fz pathways.
Science's STKE : signal transduction knowledge environment May, 2005 | Pubmed ID: 15886387
Function of the ETS transcription factor Yan in border cell migration.
Development (Cambridge, England) Aug, 2005 | Pubmed ID: 16014514
Genome-wide RNAi screen for host factors required for intracellular bacterial infection.
Science (New York, N.Y.) Aug, 2005 | Pubmed ID: 16020693
Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection.
Science (New York, N.Y.) Aug, 2005 | Pubmed ID: 16020694
Super-size flies.
Cell metabolism May, 2005 | Pubmed ID: 16054074
Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila.
Genes & development Aug, 2005 | Pubmed ID: 16055650
Norbert Perrimon.
Current biology : CB Jul, 2005 | Pubmed ID: 16059997
Heparan sulphate proteoglycans: the sweet side of development.
Nature reviews. Molecular cell biology Jul, 2005 | Pubmed ID: 16072037
Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E.
Cellular signalling Jun, 2006 | Pubmed ID: 16129580
BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.
Developmental cell Nov, 2005 | Pubmed ID: 16256740
A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway.
Nature genetics Dec, 2005 | Pubmed ID: 16311596
Evidence that stem cells reside in the adult Drosophila midgut epithelium.
Nature Jan, 2006 | Pubmed ID: 16340959
FlyRNAi: the Drosophila RNAi screening center database.
Nucleic acids research Jan, 2006 | Pubmed ID: 16381918
Functional genomics reveals genes involved in protein secretion and Golgi organization.
Nature Feb, 2006 | Pubmed ID: 16452979
High-throughput RNAi screening in cultured cells: a user's guide.
Nature reviews. Genetics May, 2006 | Pubmed ID: 16607398
Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo.
Current biology : CB Jun, 2006 | Pubmed ID: 16782008
High-throughput approaches to dissecting MAPK signaling pathways.
Methods (San Diego, Calif.) Nov, 2006 | Pubmed ID: 16844385
The emergence of geometric order in proliferating metazoan epithelia.
Nature Aug, 2006 | Pubmed ID: 16900102
Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.
Nature methods Oct, 2006 | Pubmed ID: 16964256
Minimizing the risk of reporting false positives in large-scale RNAi screens.
Nature methods Oct, 2006 | Pubmed ID: 16990807
GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo.
Gene expression patterns : GEP Jan, 2007 | Pubmed ID: 17008134
COPI activity coupled with fatty acid biosynthesis is required for viral replication.
PLoS pathogens Oct, 2006 | Pubmed ID: 17040126
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling.
Nature Nov, 2006 | Pubmed ID: 17086199
Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens.
Drug discovery today Jan, 2007 | Pubmed ID: 17198970
Applications of high-throughput RNA interference screens to problems in cell and developmental biology.
Genetics Jan, 2007 | Pubmed ID: 17244760
Genetic screening for signal transduction in the era of network biology.
Cell Jan, 2007 | Pubmed ID: 17254958
Do-it-yourself RNAi made easy?
Nature methods Apr, 2007 | Pubmed ID: 17396126
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression.
Proceedings of the National Academy of Sciences of the United States of America May, 2007 | Pubmed ID: 17517653
Quantitative morphological signatures define local signaling networks regulating cell morphology.
Science (New York, N.Y.) Jun, 2007 | Pubmed ID: 17588932
Design and implementation of high-throughput RNAi screens in cultured Drosophila cells.
Nature protocols , 2007 | Pubmed ID: 17853882
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila.
Genome biology , 2007 | Pubmed ID: 17903264
Functional screening identifies miR-315 as a potent activator of Wingless signaling.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2007 | Pubmed ID: 17989227
Drosophila and the genetics of the internal milieu.
Nature Nov, 2007 | Pubmed ID: 17994083
SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth.
Developmental cell Dec, 2007 | Pubmed ID: 18061565
In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography.
Nature methods Jan, 2008 | Pubmed ID: 18066071
Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster.
Nature methods Jan, 2008 | Pubmed ID: 18084299
Cellular phenotype recognition for high-content RNA interference genome-wide screening.
Journal of biomolecular screening Jan, 2008 | Pubmed ID: 18227224
ESCRT factors restrict mycobacterial growth.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18287038
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes.
Nature genetics Apr, 2008 | Pubmed ID: 18311141
RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance.
Development (Cambridge, England) Apr, 2008 | Pubmed ID: 18359903
An endogenous small interfering RNA pathway in Drosophila.
Nature Jun, 2008 | Pubmed ID: 18463631
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.
BMC bioinformatics , 2008 | Pubmed ID: 18534020
An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling.
Journal of biomedical informatics Feb, 2009 | Pubmed ID: 18547870
Identification of neural outgrowth genes using genome-wide RNAi.
PLoS genetics Jul, 2008 | Pubmed ID: 18604272
Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning.
Development (Cambridge, England) Aug, 2008 | Pubmed ID: 18614578
Developmental biology: Our fly cousins' gut.
Nature Jul, 2008 | Pubmed ID: 18668098
Matter arising: off-targets and genome-scale RNAi screens in Drosophila.
Fly Jan-Feb, 2007 | Pubmed ID: 18705022
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds.
Science (New York, N.Y.) Oct, 2008 | Pubmed ID: 18927396
Comparative analysis of argonaute-dependent small RNA pathways in Drosophila.
Molecular cell Nov, 2008 | Pubmed ID: 19026789
Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila.
Development (Cambridge, England) Mar, 2009 | Pubmed ID: 19211682
Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model.
Disease models & mechanisms May-Jun, 2009 | Pubmed ID: 19380309
A Drosophila resource of transgenic RNAi lines for neurogenetics.
Genetics Aug, 2009 | Pubmed ID: 19487563
RNAiCut: automated detection of significant genes from functional genomic screens.
Nature methods Jul, 2009 | Pubmed ID: 19564846
Droplet microfluidic technology for single-cell high-throughput screening.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19617544
The twin spot generator for differential Drosophila lineage analysis.
Nature methods Aug, 2009 | Pubmed ID: 19633664
Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform.
RNA (New York, N.Y.) Oct, 2009 | Pubmed ID: 19635780
Cross-species RNAi rescue platform in Drosophila melanogaster.
Genetics Nov, 2009 | Pubmed ID: 19720858
Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening.
Nature protocols , 2009 | Pubmed ID: 19798083
Homeostasis in infected epithelia: stem cells take the lead.
Cell host & microbe Oct, 2009 | Pubmed ID: 19837370
Hierarchical rules for Argonaute loading in Drosophila.
Molecular cell Nov, 2009 | Pubmed ID: 19917252
Synergy between bacterial infection and genetic predisposition in intestinal dysplasia.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2009 | Pubmed ID: 19934041
Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling.
Journal of biomolecular techniques : JBT Dec, 2009 | Pubmed ID: 19949701
A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila.
Genetics Apr, 2010 | Pubmed ID: 20100940
Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen.
Genome research Mar, 2010 | Pubmed ID: 20144944
Genomic screening with RNAi: results and challenges.
Annual review of biochemistry , 2010 | Pubmed ID: 20367032
Realizing the promise of RNAi high throughput screening.
Developmental cell Apr, 2010 | Pubmed ID: 20412765
In vivo RNAi: today and tomorrow.
Cold Spring Harbor perspectives in biology Aug, 2010 | Pubmed ID: 20534712
Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.
PLoS genetics Jun, 2010 | Pubmed ID: 20585550
Steroids make you bigger? Fat chance says Myc.
Cell metabolism Jul, 2010 | Pubmed ID: 20620990
A genome-wide gene function prediction resource for Drosophila melanogaster.
PloS one , 2010 | Pubmed ID: 20711346
Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRs.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2010 | Pubmed ID: 20729470
作为一种模型系统研究自噬的果蝇。
Seminars in immunopathology Dec, 2010 | Pubmed ID: 20798940
Identification of adult midgut precursors in Drosophila.
Gene expression patterns : GEP Jan-Feb, 2011 | Pubmed ID: 20804858
Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis.
Development (Cambridge, England) Nov, 2010 | Pubmed ID: 20940225
The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration.
Development (Cambridge, England) Dec, 2010 | Pubmed ID: 21098564
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging.
Cell Nov, 2010 | Pubmed ID: 21111239
Sarcomere formation occurs by the assembly of multiple latent protein complexes.
PLoS genetics Nov, 2010 | Pubmed ID: 21124995
All for one, and one for all: the clonality of the intestinal stem cell niche.
F1000 biology reports , 2010 | Pubmed ID: 21173846
The transcriptional diversity of 25 Drosophila cell lines.
Genome research Feb, 2011 | Pubmed ID: 21177962
Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence.
Genome research Feb, 2011 | Pubmed ID: 21177969
Identification of functional elements and regulatory circuits by Drosophila modENCODE.
Science (New York, N.Y.) Dec, 2010 | Pubmed ID: 21177974
The developmental transcriptome of Drosophila melanogaster.
Nature Mar, 2011 | Pubmed ID: 21179090
Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila.
Wiley interdisciplinary reviews. Systems biology and medicine Jul-Aug, 2011 | Pubmed ID: 21197652
A genome-wide RNAi screen identifies core components of the Gâ‚‚-M DNA damage checkpoint.
Science signaling , 2011 | Pubmed ID: 21205937
False negative rates in Drosophila cell-based RNAi screens: a case study.
BMC genomics , 2011 | Pubmed ID: 21251254
Intelligent Interfaces for Mining Large-Scale RNAi-HCS Image Databases.
Proceedings / Annual IEEE International Symposium on Bioinformatics and Bioengineering (BIBE). IEEE International Symposium on Bioinformatics and Bioengineering Nov, 2007 | Pubmed ID: 21278820
Control of the mitotic cleavage plane by local epithelial topology.
Cell Feb, 2011 | Pubmed ID: 21295702
Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
Human molecular genetics May, 2011 | Pubmed ID: 21300695
A genome-scale shRNA resource for transgenic RNAi in Drosophila.
Nature methods May, 2011 | Pubmed ID: 21460824
Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs.
Genome research Sep, 2011 | Pubmed ID: 21685129
Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis.
Developmental cell Jul, 2011 | Pubmed ID: 21763605
An integrative approach to ortholog prediction for disease-focused and other functional studies.
BMC bioinformatics , 2011 | Pubmed ID: 21880147
Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype.
The Journal of cell biology Sep, 2011 | Pubmed ID: 21893601
RNAi screening: new approaches, understandings, and organisms.
Wiley interdisciplinary reviews. RNA Sep, 2011 | Pubmed ID: 21953743
Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling.
Science signaling , 2011 | Pubmed ID: 22028469
FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update.
Nucleic acids research Jan, 2012 | Pubmed ID: 22067456
The era of systems developmental biology.
Current opinion in genetics & development Dec, 2011 | Pubmed ID: 22079435
Stringent Analysis of Gene Function and Protein-Protein Interactions Using Fluorescently Tagged Genes.
Genetics Dec, 2011 | Pubmed ID: 22174071
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