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University Hospital Essen

3 ARTICLES PUBLISHED IN JoVE

Medicine

Real-time Pressure-volume Analysis of Acute Myocardial Infarction in Mice

Lars Michel¹, Pia Stock¹, Christos Rammos¹, Matthias Totzeck¹, Tienush Rassaf¹, Ulrike B. Hendgen-Cotta¹

¹West German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, Medical Faculty, University Hospital Essen

Acute myocardial infarction in mice induces acute but incompletely characterized changes in left ventricular (LV) function. LV catheterization in mice undergoing coronary artery occlusion serves as a novel method for a real-time evaluation of LV function.

Medicine

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

Catherine Parmentier¹, Samrat Ray¹, Laura Mazilescu^1,2, Masataka Kawamura¹, Yuki Noguchi¹, Emmanuel Nogueira¹, Sujani Ganesh¹, Bhranavi Arulratnam¹, Sangeetha Kalimuthu³, Markus Selzner¹, Trevor Reichman¹

¹Ajmera Transplant Program, University Health Network, Toronto General Hospital, ²Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, ³Department of Pathology, University Health Network, Toronto General Hospital

Normothermic ex vivo machine perfusion (NEVP) has scarcely been explored for the preservation of pancreas allografts. We present an innovative preservation technique for pancreas allografts before transplantation.

Medicine

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

Samrat Ray¹, Catherine Parmentier¹, Laura Mazilescu^1,2, Masataka Kawamura¹, Yuki Noguchi¹, Emmanuel Nogueira¹, Sujani Ganesh¹, Bhranavi Arulratnam¹, Markus Selzner¹, Trevor Reichman¹

¹Ajmera Transplant Centre, University Health Network, Toronto general hospital, ²Department of general, visceral, and transplantation surgery, University Hospital Essen

The video article summarizes the technique of pancreatectomy and pancreas allotransplantation in a porcine 3-day survival model with a step-by-step description of the method and emphasis on the surgical tips and tricks to deal with the precarious and delicate porcine visceral anatomy.