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Christopher Newport University

2 ARTICLES PUBLISHED IN JoVE

Behavior

Place and Response Learning in the Open-field Tower Maze

Olga Lipatova¹, Matthew M. Campolattaro¹, Donna J. Toufexis², Erin A. Mabry¹

¹Department of Psychology, Christopher Newport University, ²Department of Psychological Science, University of Vermont

The Open-field Tower Maze (OFTM) is a maze created to study the behavioral and neural mechanisms of spatial learning (e.g., place- or response-learning) in rats. This maze is especially useful for experimenters who want to use a non-stressful maze paradigm to investigate spatial learning in their research.

Biochemistry

DNA Electrophoresis Using Thiazole Orange Instead of Ethidium Bromide or Alternative Dyes

Casey S. O’Neil¹, Jacie L. Beach¹, Todd D. Gruber¹

¹Department of Molecular Biology and Chemistry, Christopher Newport University

Here, we present a protocol to use thiazole orange for the detection of DNA in gel electrophoresis experiments. The use of thiazole orange allows elimination of ethidium bromide, and fluorescence detection can be achieved with either UV or blue light.