Yantai University
2 ARTICLES PUBLISHED IN JoVE
Neuroscience
Quantitative Cell Biology of Neurodegeneration in Drosophila Through Unbiased Analysis of Fluorescently Tagged Proteins Using ImageJ
Jennifer M. Brazill 1, Yi Zhu 1, Chong Li 1, R. Grace Zhai 1,2
1Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, 2School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University
We have developed a simple and adaptable workflow to extract quantitative data from fluorescence-imaging-based cell biological studies of protein aggregation and autophagic flux in the central nervous system of Drosophila models of neurodegeneration.
Neuroscience
A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels
Zhang Jiren 1, Jia Xue 2, Sun Yufei 2, Li Huiwen 2, Yang Jian 1, Qi Shilei 1, Zhao Dongman 1, Xie Lei 1, Jia Mingming 1, Wang Tian 2, Zhang Pinyuan 1
1Department of Neurosurgery, The Third Hospital of Hebei Medical University, 2School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University
The current protocol describes a rat model of middle cerebral artery occlusion/reperfusion that preserves the anatomical structure of cerebral vessels without causing damage.
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