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China-Japan Union Hospital of Jilin University

5 ARTICLES PUBLISHED IN JoVE

Cancer Research

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Xin Feng¹, Shaofei Wang¹, Quewang Liu¹, Han Li², Jiamei Liu², Cheng Xu², Weifeng Yang², Yayun Shu², Weiwei Zheng¹, Bingxin Yu³, Mingran Qi⁴, Wenyang Zhou¹, Fengfeng Zhou¹

¹College of Computer Science and Technology, and Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education, Jilin University, ²College of Software, Jilin University, ³Ultrasonography Department, China-Japan Union Hospital of Jilin University, ⁴Department of Pathogenobiology, College of Basic Medical Science, Jilin University

Existing algorithms generate one solution for a biomarker detection dataset. This protocol demonstrates the existence of multiple similarly effective solutions and presents a user-friendly software to help biomedical researchers investigate their datasets for the proposed challenge. Computer scientists may also provide this feature in their biomarker detection algorithms.

Medicine

Establishing In Situ Closed Circuit Perfusion of Lower Abdominal Organs and Hind Limbs in Mice

Ping Ren^1,2,3, Chunyan Yang^2,4, Laren A. Lofchy², Guankui Wang², Fangfang Chen^*2,4,5, Dmitri Simberg^*2

¹Department of Thoracic Surgery, The First Hospital of Jilin University, ²The Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, ³Key Laboratory of Zoonoses Research, Ministry of Education, Jilin University, ⁴Department of Cardiology, China-Japan Union Hospital of Jilin University, ⁵Department of Gastrointestinal, Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University

A protocol is described for in situ perfusion of the mouse lower body, including the bladder, the prostate, sex organs, bone, muscle and foot skin.

Biology

Microsurgical Obstruction of Testes Fusion in Spodoptera litura

Xiaolin He^*1, Qianqian Ma^*1, Baozhu Jian¹, Yucheng Liu¹, Qiong Wu¹, Meixin Chen¹, Qili Feng¹, Ping Zhao², Lin Liu¹

¹South China Normal University-Shipai Campus: South China Normal University, ²Southwest University

Aluminum foil was microsurgically inserted between the testes of Spodoptera litura to obstruct the fusion of testis. The procedure includes freezing, fixing, disinfection, incision, placing the barrier, suturing, postoperative feeding, and inspection. This approach provides a method to interfere with tissue formation.

Medicine

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Yanjing Wang¹, Hang Gao¹, Yi Li¹, Huan Sun^*2, Lin Liu^*1

¹Radiology Department, China-Japan Union Hospital of Jilin University, ²Cardiology Department, China-Japan Union Hospital of Jilin University

The atrial function is associated with the strain and strain rate. The cardiac magnetic resonance feature tracking (CMR-FT) technique was used in this study to quantify left and right atrial global and segmental longitudinal strain and strain rate in individuals with paroxysmal atrial fibrillation.

Medicine

Three-Dimensional Modeling of the Left Atrium and Pulmonary Veins with a Precise Intracardiac Echocardiography Approach

Xue Xia¹, Huan Sun¹, Xiuming Zhou², Daoyuan Si¹, Qini Zhao¹, Yuquan He¹, Hongliang Yang¹

¹Cardiology Department, China-Japan Union Hospital of Jilin University, ²Qianwei Hospital of Jilin Province

Accurate intracardiac echocardiography (ICE) shows significant accuracy in estimating the left atrial structure, a prospective and promising cardiac structure estimation method. Here we propose a protocol for three-dimensional modeling of the left atrium and pulmonary veins with ICE and fast anatomical mapping (FAM) catheter remodeling.