Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay SystemKazuma Sekiba 1,2, Motoyuki Otsuka 1, Kazuhiko Koike 1
1Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 2Research Fellow of Japan Society for the Promotion of Science
Here, we present a method for screening anti-hepatitis B viral agents that inhibit the HBx-DDB1 interaction using a split luciferase assay system. This system allows easy detection of protein-protein interactions and is suitable for identifying inhibitors of such interactions.
