In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized tasks—to detect specific elements, functional groups, or trace analytes that general-purpose detectors cannot effectively measure.

Thermionic detectors are selective towards organic compounds containing phosphorus and nitrogen. Compared to the FID, they are highly sensitive to phosphorus-containing compounds, making them helpful in detecting organophosphate pesticides. Thermionic detectors operate by igniting the column effluent mixed with hydrogen, passing it through a flame, and then flowing the hot gas around an electrically heated rubidium silicate bead, which enhances the detection sensitivity.

The Hall electrolytic conductivity detector detects compounds containing halogens, sulfur, or nitrogen. The compounds are mixed with a reaction gas at high temperatures within a reactor tube. The resulting products are dissolved in a conductive solution, and the change in conductivity is measured. Depending on the specific reaction gas and the conductivity solvent, different operational modes, such as halogen, sulfur, and nitrogen modes, are used.

The photoionization detector utilizes ultraviolet radiation from a hydrogen or argon lamp to photoionize the molecules eluting from the GC column. Compounds with lower ionization potentials are easily ionized and detected, while those with higher ionization potentials are less detectable. The ions and electrons produced by photoionization are collected at biased electrodes, making this detector particularly sensitive to aromatic hydrocarbons and certain organosulfur or organophosphorus compounds.

Atomic emission detectors (AED) use microwave-induced plasma (MIP), inductively coupled plasma (ICP), or direct current plasma (DCP) to atomize and excite the elements present in the sample. AEDs are element-selective and can simultaneously monitor several elements. Diode array or charge-coupled device atomic emission spectrometers are commonly used with the MIP to analyze the emitted atomic spectra.

The flame photometric detector (FPD) primarily responds to compounds containing sulfur and phosphorus. The eluent is passed through a low-temperature hydrogen-air flame, converting phosphorus to an HPO species, which emits characteristic radiation. Suitable filters isolate the specific emission bands, and their intensity is measured photometrically. FPD is widely used for analyzing air and water pollutants, pesticides, and coal hydrogenation products.

The choice of detector depends on the analysis's requirements. Each detector is designed with technical precision to ensure accurate and reliable results in various applications.