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Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats

DOI :

10.3791/237-v

July 19th, 2007

July 19th, 2007

17,359 Views

1Department of Physiology and Biophysics, University of California, Irvine (UCI)

Delayed type hypersensitivity (DTH) is an inflammatory reaction mediated by CCR7- effector memory T lymphocytes. Here we demonstrate how to induce active DTH in Lewis rats and monitor the inflammatory response.

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