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Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures

DOI :

10.3791/2949-v

16:01 min

August 1st, 2011

August 1st, 2011

25,882 Views

1Section on Critical Brain Dynamics, National Institute of Mental Health

A robust way to study neuronal avalanches, i.e. scale-invariant spatio-temporal activity bursts, indicative of critical state dynamics in cortex. Avalanches emerge spontaneously in developing superficial layers of cultured cortex which allows for long-term measurements of the activity with planar integrated multi-electrode arrays (MEA) under precisely controlled conditions.

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Multi electrode Array Recordings

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