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Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

DOI :

10.3791/3893-v

August 24th, 2012

August 24th, 2012

24,765 Views

1Departments of Psychiatry and Neuroscience, and Friedman Brain Institute, Mt. Sinai School of Medicine, 2Department of Psychology, New York University , 3Department of Psychology and Center for Neural Science, New York University

Conditioned fear can be diminished through an inhibitory process called extinction, but can resurface under conditions such as the passage of time or exposure to stress. Our protocol presents a novel way of preventing fear recovery by introducing extinction during the reconsolidation window (the re-storage phase of a reactivated memory).

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