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Three-dimensional Cell Culture Model for Measuring the Effects of Interstitial Fluid Flow on Tumor Cell Invasion

DOI :

10.3791/4159-v

July 25th, 2012

July 25th, 2012

16,275 Views

1School of Biomedical Engineering, Science and Health Systems, Drexel University

Interstitial fluid flow is elevated in solid tumors and can modulate tumor cell invasion. Here we describe a technique to apply interstitial fluid flow to cells embedded in a matrix and then measure its effects on cell invasion. This technique can be easily adapted to study other systems.

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Three dimensional Cell Culture

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