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Simultaneous Intracellular Recording of a Lumbar Motoneuron and the Force Produced by its Motor Unit in the Adult Mouse In vivo

DOI :

10.3791/4312-v

December 5th, 2012

December 5th, 2012

14,432 Views

1Department of Physiology, Northwestern University Feinberg School of Medicine

This new method permits the simultaneous intracellular recording of a single adult mouse motoneuron and the measurement of the force produced by its muscle fibers. The combined investigation of the electrical and mechanical properties of motor units in normal and genetically modified animals is a breakthrough for the study of the neuromuscular system.

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Simultaneous Intracellular Recording

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