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Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

DOI :

10.3791/50004-v

October 29th, 2012

October 29th, 2012

43,373 Views

1Department of Molecular & Human Genetics, Baylor College of Medicine (BCM), 2Department of Neuroscience, Baylor College of Medicine (BCM), 3Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital

The development of optogenetics now provides the means to precisely stimulate genetically defined neurons and circuits, both in vitro and in vivo. Here we describe the assembly and implantation of a fiber optic for chronic photostimulation of brain tissue.

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