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Optogenetic Stimulation of Escape Behavior in Drosophila melanogaster

DOI :

10.3791/50192-v

January 25th, 2013

January 25th, 2013

16,840 Views

1Department of Neurobiology, Stanford University

Genetically encoded optogenetic tools enable noninvasive manipulation of specific neurons in the Drosophila brain. Such tools can identify neurons whose activation is sufficient to elicit or suppress particular behaviors. Here we present a method for activating Channelrhodopsin2 that is expressed in targeted neurons in freely walking flies.

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