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Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue

DOI :

10.3791/50126-v

11:31 min

February 11th, 2013

February 11th, 2013

16,433 Views

1Weldon School of Biomedical Engineering, Purdue University, 2Department of Biological Sciences, Purdue University

Here we present a histological method for capturing, labeling, optically clearing, and imaging the intact brain tissue interface around chronically implanted microdevices in rodent brain tissue. Results from the techniques comprising this method are useful for understanding the impact of various penetrating brain-implants on their surrounding tissue.

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Brain implanted Microdevices

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