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Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

DOI :

10.3791/51081-v

9:43 min

October 31st, 2013

October 31st, 2013

12,914 Views

1Department of Physics, University of Ottawa, 2Ottawa-Carleton Institute of Biomedical Engineering, University of Ottawa

A methodology for preparing solid-state nanopores in solution for biomolecular translocation experiments is presented. By applying short pulses of high electric fields, the nanopore diameter can be controllably enlarged with subnanometer precision and its electrical noise characteristics significantly improved. This procedure is performed in situ using standard laboratory equipment under experimental conditions.

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Solid state Nanopores

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