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Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation

DOI :

10.3791/51695-v

July 23rd, 2014

July 23rd, 2014

18,592 Views

1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital

In order to understand the cellular and molecular mechanisms underlying neotissue formation and stenosis development in tissue engineered heart valves, a murine model of heterotopic heart valve transplantation was developed. A pulmonary heart valve was transplanted to recipient using the heterotopic heart transplantation technique.

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Keywords Pulmonary Valve Transplantation

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